CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041783
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 3-ketoacyl-CoA thiolase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Acaa2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
13GVFIVAAKRTPFGAYacetylation[1]
25GAYGGLLKDFTATDLacetylation[1]
137RNVRFGTKFGLDLKLacetylation[1]
158GLTDQHVKLPMGMTAacetylation[1]
171TAENLAAKYNISREDacetylation[1]
191LQSQQRWKAANEAGYacetylation[1]
209EMAPIEVKTKKGKQTacetylation[1]
214EVKTKKGKQTMQVDEacetylation[1]
269IASEDAVKKHNFTPLacetylation[1]
270ASEDAVKKHNFTPLAacetylation[1]
305PAITGALKKAGLSLKacetylation[1]
312KKAGLSLKDMDLIDVacetylation[1]
340SLDLDPSKTNVSGGAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 396 AA 
Protein Sequence
MALLRGVFIV AAKRTPFGAY GGLLKDFTAT DLTEFAARAA LSAGKVPPET IDSVIVGNVM 60
QSSSDAAYLA RHVGLRVGVP TETGALTLNR LCGSGFQSIV SGCQEICSKD AEVVLCGGTE 120
SMSQSPYSVR NVRFGTKFGL DLKLEDTLWA GLTDQHVKLP MGMTAENLAA KYNISREDCD 180
RYALQSQQRW KAANEAGYFN EEMAPIEVKT KKGKQTMQVD EHARPQTTLE QLQKLPPVFK 240
KEGTVTAGNA SGMSDGAGVV IIASEDAVKK HNFTPLARVV GYFVSGCDPA IMGIGPVPAI 300
TGALKKAGLS LKDMDLIDVN EAFAPQFLAV QKSLDLDPSK TNVSGGAIAL GHPLGGSGSR 360
IAHLVHELRR RGGKYAVGSA CIGGGQGISL IIQNTA 396 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara. 
Interpro
 IPR002155; Thiolase.
 IPR016039; Thiolase-like.
 IPR016038; Thiolase-like_subgr.
 IPR020615; Thiolase_acyl_enz_int_AS.
 IPR020610; Thiolase_AS.
 IPR020617; Thiolase_C.
 IPR020613; Thiolase_CS.
 IPR020616; Thiolase_N. 
Pfam
 PF02803; Thiolase_C
 PF00108; Thiolase_N 
SMART
  
PROSITE
 PS00098; THIOLASE_1
 PS00737; THIOLASE_2
 PS00099; THIOLASE_3 
PRINTS