CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035657
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Filamin, beta (Predicted) 
Protein Synonyms/Alias
 Protein Flnb 
Gene Name
 Flnb 
Gene Synonyms/Alias
 Flnb_predicted; rCG_42230 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
502KGLEELVKQKGFLDGacetylation[1]
681DAGNAPLKILAQDGEacetylation[1]
697QPIDIQMKSRMDGTYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2578 AA 
Protein Sequence
MPVTEKDLAE DAPWKKIQQN TFTRWCNEHL KCVNKRIGNL QTDLSDGLRL IALLEVLSQK 60
RMHHKYHQRP TFRQMKLENV SVALEFLDHE SIKLVSIDSK AIVDGNLKLI LGLVWTLILH 120
YSISMPVWED EGDDDAKKQT PKQRLLGWIQ NKIPYLPITN FNQNWQDGKA LGALVDSCAP 180
GLCPDWESWD PRKPVDNARE AMQQADDWLG VPQVITPEEI IHPDVDEHSV MTYLSQFPKA 240
KLKPGAPLKP KLNPKKARAY GRGIESTGNM VKQPAKFTVD TISAGQGDVM VFVEDPEGNK 300
EEARVTPDSD KNKTYSVEYL PKVTGLHKVI VLFAGQHISK SPFEVNVDKA QGDASKVTAK 360
GPGLETTGNI ANKPTYFDIY TAGAGVGDIG VEVEDPQGKN SVELLVEDRG NQVYRCVYKP 420
LQPGPHVVKV SFAGDAIPKS PFGVQIGEAC NPNACRASGR GLQPKGVRIR ETADFKVDTK 480
AAGSGELAVT VKGPKGLEEL VKQKGFLDGV YSFEYYPSTP GKYSIAVTWG GHHIPKSPFE 540
VQVGPEAGMQ KVRAWGPGLH GGIVGRSADF VVESIGSEVG TLGFAIEGPS QAKIEYDDQN 600
DGSCDVKYWP KEPGEYAVHI MCDDEDIKDS PYMAFIHPAT GDYNPDLVQA YGPGLEKTGC 660
TINNPAEFIV DPKDAGNAPL KILAQDGEGQ PIDIQMKSRM DGTYVCSYTP VKAIKHTIAV 720
VWGGVNIPHS PYRVNIGQGS HPQKVKVFGP GVERSGLKAN EPTHFTVDCT EAGEGDVSVG 780
IKCDARVLSD DEEDVDFDII HNANDTFTVK YVPPAPGRYT IKVLFASEEI PASPFRVKVD 840
PSHDASKVKA EGPGLSKAGV ENGKPTHFTV HTKGAGKAPL NVQFSSPVPG EAVKDLDIID 900
NYDYSHTVKY TPTQQGNMQV LVTYGGDPIP KSPFTVGVAA PLDLSKIKIN GLENRVEVGK 960
DQEFAIDTNG AGGQGKLDVT ILSPSRKVVP CLVAPVAGRE CSTAKFIPRE EGLFAVDVTY 1020
DGHPVPGSPY TVEASLPPDP TKVKAHGPGL EGGLVGKPAE FTIDTKGAGT GGLGLTVEGP 1080
CEAKIECSDN GDGTCSVSYL PTKPGEYFVN ILFEEVHIPG SPFKADIEMP FDPSKVVASG 1140
PGLEHGKVGE PGILCVDCSE AGPGTLGLEA VSDSGAKAEV SIQNNKDGSY AVTYVPLTAG 1200
MYTLTMKYGG ELVPQFPTWV KVEPTVDTSG IKAFGPGIEG KDVFREATTD FTVDARPLTQ 1260
VGGDHIKAHI ANPSGASTEC FVKDNADGTY QVEYTPFEKG FHVVEVTYDD APIPNSPFKV 1320
AVNEGCQPSR VHAQGPGLKE AFTNKPNVFT VVTRGAGIGG LGITVEGPSE SKINCRDNKD 1380
GSCSAEYIPF APGDYDVNIT YGGVHIPGSP FRVPSKDVVD PSKVKIAGPG LSSCVRACIP 1440
QSFTVDTSKA GLAPLEVRVM GPRGLVEPVD VVDNGDGTHT VTYTPSQEGP YIVSVKYADE 1500
EIPRSPFKVK VLPTYDASKV TASGPGLSAY GVPASLPVEF AIDARDAGEG LLAVQITDQE 1560
GKPQRATVHD NKDGTYAVTY IPDKTGRYMI GVTYGGDNIP LSPYRIRATQ TGDASKCLAT 1620
GPGIAPTVKT GEEVGFVVDA KTAGKGKVTC VILTPDGTEA EADVIENEDG TYDIFYTAAK 1680
PGTYVIYVRF GGVDIPNSPF TVMVTEEAYV PVSDMNGLGF KPFDLVIPFA VRKGEITGQV 1740
HMPSGKKATP EIVDNKDGTV TVRYAPTEVG LHEMHIKYMG SHIPESPLQF YVNYPNSGSV 1800
SAYGPGLVYG VANKTATFTI VTEDAGEGGL DLAIEGPSKA EISCIDNKDG TCTVTYLPTL 1860
PGDYSILVKY NDKHIPGSPF TAKITDDSRR CSQVKLGSAA DFLLDISETD LSTLTASIKA 1920
PSGRDEPCLL KRLPNNHIGI SFIPREVGEH LVSIKKNGNH VANSPVSIMV VQSEIGDARR 1980
AKVYGRGLSE GRTFEMSDFI VDTRDAGYGG ISLAVEGPSK VDIQTEDLED GTCKVSYFPT 2040
VPGVYIVSTK FADEHVPGSP FTVKISGEGR VKESITRTSR APSVATVGSI CDLNLKIPEI 2100
NSSDMSAHVT SPSGHVTEAE IVPVGKNSHC VRFVPQEMGV HTVSVKYRGQ HVTGSPFQFT 2160
VGPLGEGGAH KVRAGGPGLE RGEAGIPAEF SIWTREAGAG GLSIAVEGPS KAEITFDDHK 2220
NGSCGVSYIA QEPGNYEVSI KFNDEHIPDS PYLVPVIAPS DDARCLTVLS LQESGLKVNQ 2280
PASFAIRLNG AKGKIDAKVH SPSGAVEECH VSELEPDKYA VRFIPHENGI HTIDVKFNGS 2340
HVVGSPFKVR VGEPGQAGNP ALVSAYGAGL EAGTTGIQSE FFINTTQAGP GTLSVTIEGP 2400
SKVKMDCQEI PEGYKVMYTP MAPGNYLISV KYGGPNHISR SPFKAKVTGQ RLVTPGSANE 2460
TSSILVESVT RSSTETCYSA IPKSSSDASK VTSKGAGLSK AFVGQKSSFL VDCSKAGSNM 2520
LLIGVHGPTT PCEEVSMKHV GKQQYNVTYV VKEKGDYVLA VKWGEEHIPG SPFHVTVP 2578 
Gene Ontology
  
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set. 
Pfam
 PF00307; CH
 PF00630; Filamin 
SMART
 SM00033; CH
 SM00557; IG_FLMN 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS50194; FILAMIN_REPEAT 
PRINTS