UniProt Accession

 MPCP_MOUSE; Q8VEM8; Q542V7 

Genbank Protein ID

 AK077274; AK077723; AK088013; AK150641; AK150729; AK150870; AK151518; AK152006; AK152292; AK152341; AK167197; AK168580; BC018161 

Genbank Nucleotide ID

 BAC36723.1; BAC36982.1; BAC40095.1; BAE29729.1; BAE29806.1; BAE29921.1; BAE30467.1; BAE30870.1; BAE31101.1; BAE31137.1; BAE39327.1; BAE40449.1; AAH18161.1 

Protein Name

 Phosphate carrier protein, mitochondrial 

Protein Synonyms/Alias

 Phosphate transport protein; PTP; Solute carrier family 25 member 3 

Gene Name

 Slc25a3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
94	RMQVDPQKYKGIFNG	acetylation	[1]
201	TLREAVPKMYKEEGL	acetylation	[2]
204	EAVPKMYKEEGLNAF	acetylation	[1, 2]
229	QIPYTMMKFACFERT	acetylation	[2]
242	RTVEALYKFVVPKPR	acetylation	[2]

Reference

 [1] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Transport of phosphate groups from the cytosol to mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) (By similarity). 

Sequence Annotation

 REPEAT 58 142 Solcar 1.
 REPEAT 155 239 Solcar 2.
 REPEAT 256 334 Solcar 3.
 MOD_RES 94 94 N6-acetyllysine.
 MOD_RES 191 191 Phosphotyrosine (By similarity).
 MOD_RES 204 204 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Repeat; Symport; Transit peptide; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 357 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0015293; F:symporter activity; IEA:UniProtKB-KW. 

Interpro

 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 

Pfam

 PF00153; Mito_carr 

SMART

  

PROSITE

 PS50920; SOLCAR 

PRINTS