CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010023
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Uncharacterized ATP-dependent helicase MPN_020 
Protein Synonyms/Alias
  
Gene Name
 MPN_020; D12_orf1030, MP134 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
252VCGFSGKKVFDFVTYacetylation[1]
260VFDFVTYKQKEKQIVacetylation[1]
350FVSDAFFKYKNHFNKacetylation[1]
765QFTDQFEKEKTDQSFacetylation[1]
793RTKSKVLKELPNKITacetylation[1]
923SRHSIIEKFNNAKNPacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
  
Sequence Annotation
 DOMAIN 590 751 Helicase ATP-binding.
 DOMAIN 867 1021 Helicase C-terminal.
 ZN_FING 51 86 SWIM-type.
 NP_BIND 603 610 ATP (Potential).
 MOTIF 702 705 DEAQ box.  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Metal-binding; Nucleotide-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1030 AA 
Protein Sequence
MTIAEIRKFA QTTQKFVEAE NLFEHGNVVL PKKYLNKARG MAEVLYNSQV IKVSFTAKDG 60
ELTCKCSCLA NVDNCVHIVA VLLKYHQMLV ESKRSFNLAE AFHLDCDQAE MLIENLSLEI 120
IAGGWNFKLG FTINLDKHNP QPSVLRFYCC DATFVYFLHL ENDTLHSVEL SKFKPEERAT 180
LLFFDKLCKQ FTVGYDRNSL LFPLAGFLKE LQANTEPTIF VFNDDKIDNI LFLRISKKHH 240
GLNHVCGFSG KKVFDFVTYK QKEKQIVLRS AYLSKFTDFK FPYTINIYKL QFGEPLFFYF 300
LIQLKRDGFK NFYFQSEDSI VKEKEYLPKL YFKVEYDPVK NKFVSDAFFK YKNHFNKGTT 360
TVYPHRYYMA KKSDRGGFNR LLFYEEAVEN FYQDQFDLGY FRKFEHLPIQ DKNQIEAFKA 420
ALDDLMPVDL AEVSLSDNLL HQKPLHFALS DLEAVAVDDK QIKLSFAPSA VELKLIKRIL 480
SAYHKGNVVC IDQESWYDLK QPAAKELIQF WNQFDLRNAT SDGNHIYLPK YYLFEVAKIF 540
SQYLDIKNLF DVPTIKKIED QNNNVFDLSL EHKKITSLRN YQQEGVKWIR GLEENKFGGI 600
LADEMGLGKT VQVIFALLDS YLKNHVNLPS LIIVPASLLL NWKSEFEKFA PQIKVKVANI 660
PSKERGELYE KLTNEILIVS FNVLRSDVKL ITKQRFHYVV IDEAQGIKND SSSITKAAKK 720
VKGNFCLALT GTPIENRLLD LWSCFDFVLP SFLGNKKQFT DQFEKEKTDQ SFHLLMQRTS 780
PFILRRTKSK VLKELPNKIT TDIYVELNPM HQKLYEEERD RGLEEIKQIQ DKSSFNILTL 840
ILKLRHLCSL PKNSQGILEN SAKKEAALEI IHEAIENQRK IILFTQFIDV IDHFKDTFKE 900
QGIEYFIFDG RKSPKSRHSI IEKFNNAKNP CVLLASLKAG GVGINLTAAE VVIHFDVWWN 960
TAVENQATDR AHRIGQKKTV QVYRIIAKNT IEERVCQVQA EKQELVSKTL VEDVNFFESL 1020
TNEELLRLFE 1030 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N.
 IPR007527; Znf_SWIM. 
Pfam
 PF00271; Helicase_C
 PF00176; SNF2_N
 PF04434; SWIM 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS50966; ZF_SWIM 
PRINTS