| Tag | Content |
|---|
| CPLM ID | CPLM-011845 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component |
Protein Synonyms/Alias | |
Gene Name | SNU66 |
Gene Synonyms/Alias | YOR308C; 05667 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 404 | KVHGEGEKNIGDVTN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Component of the U4/U6.U5 tri-snRNP particle, one of the building blocks of the spliceosome. Required for pre-mRNA splicing. |
Sequence Annotation | MOD_RES 268 268 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Spliceosome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 587 AA |
Protein Sequence | MNKTENLSIE ETNEIREKLG MKPIPVFQEK NTDHKESLSI EETNELRASL GLKLIPPQQN 60
FNSSPPNVHN TSKIDELREK ITKFQKKANA PLRMAHLLEE TNVNDDSSWL ENMDAIPSSH 120
ESKRSSTLPR KGATKEDENI DLHNVQVSYN IEALSPKKDT ILTLKESSIF DDTDSTEVLE 180
NVKAAEENAD REKLRLRQMN KDRRQKKKIL NVSSLDIEEE EEGEKHSITT THLIIGAEQG 240
VMKAPNTISA KPPTGKVKVN FDSANNMSDE DGGDFKPLKI KKRKIKDPRS TKARKSKITD 300
KMEIVKLVDE DESLSWMEEE QPVTIINPRT SSNNELKGPE DLAREIEKAR DEEKRRTESI 360
LKMREISNSI VVDEKVTFLN TLDTSLSERS ATENKVKVHG EGEKNIGDVT NGHTKEGSGN 420
NTLTEAVNNE PNYEGDAENA PNFFSGLAST LGYLRKKSVF TTGDVDLKPG KDVNNSESLR 480
RDVRNKEHTG TGTYTKDKLH GLEQFTSSDS SNANTHSKRQ DHYDPDIKLV YRDEKGNRLT 540
TKEAYKKLSQ KFHGTKSNKK KRAKMKSRIE ARKNTPENGS LFEFDDN 587 |
Gene Ontology | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD. GO:0000481; P:maturation of 5S rRNA; IMP:SGD. GO:0000398; P:mRNA splicing, via spliceosome; IMP:SGD. |
Interpro | |
Pfam | |
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PROSITE | |
PRINTS | |