CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033978
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 16 
Protein Synonyms/Alias
  
Gene Name
 Usp16 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
277KKRVVTPKELFSQVCubiquitination[1]
291CKKATRFKGYQQQDSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 754 AA 
Protein Sequence
MGKKRTKGRS APDTVASESA EPVCRHLRKG LEQGNLKKAL VNVEWNICQD CKTDNKVKDK 60
PEEEAEDPSV WLCLKCGHQG CGRDSQEQHA LKHYTTPRSE PHYLVLSLDN WSVWCYKCDE 120
EVKYCSSNRL GQVVDYVRKQ AGVRTSKPEK NNGHIELENK KLEKESKNEQ EREKSENLAK 180
ETIPMDSASQ ITVKGLSNLG NTCFFNAVMQ NLSQTPVLRE LLKEVKMSGT IVKIEPPDLA 240
LTEPLEVNLE PPGPLTLAMS QFLSEMQENK KRVVTPKELF SQVCKKATRF KGYQQQDSQE 300
LLRYLLDGMR AEEHQRVSKG ILKAFGNSTE KLDEEVKNKV KDYEKKKAIP SFVDRIFGGE 360
LTSTIMCDEC RTVSLVHESF LDLSLPVLDD QSGKKSINDK NVKMTMEEED KDSEEEKDDS 420
YMKSRSDLPS GTSKHLQKKA KKQAKKQAKN QRRQQKIQER FLHFNELCAT DYTEDNEREA 480
DTALAGEVEV DTDSTHGSQE EATQIELSVN QKDLDGQESM IERTPDVQES PEDLGVKSAN 540
TESDLGIVTP APECPRDFNG AFLEERTSGE LDIINGLKNL NLNAAVDPDE INIEIPNDSH 600
SAPKVYEVMN EDPETAFCTL ANREAFSTDE CSIQHCLYQF TRNEKLQDAN KLLCEVCSRR 660
QCNGPKANIK GDRRHVYTNA KKQMLVSLAP PVLTLHLKRF QQAGFNLRKV NKHIKFPEIL 720
DLAPFCTLKC KIVKWNQPKG SGFTSAIHMC KLCL 754 
Gene Ontology
 GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR001607; Znf_UBP. 
Pfam
 PF00443; UCH
 PF02148; zf-UBP 
SMART
  
PROSITE
 PS00972; UCH_2_1
 PS50235; UCH_2_3
 PS50271; ZF_UBP 
PRINTS