CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger CCCH domain-containing protein 7B 
Protein Synonyms/Alias
 Rotavirus 'X'-associated non-structural protein; RoXaN 
Gene Name
 ZC3H7B 
Gene Synonyms/Alias
 KIAA1031 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
83LPRELLCKLHVNRAAubiquitination[1]
549FDPLGGVKRGSLTIAubiquitination[1]
784IHAQNGRKCQYVGNCubiquitination[1]
807RDMWTFMKENKILDMubiquitination[1]
829LKKHNPGKPGEGTPIubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 REPEAT 36 69 TPR 1.
 REPEAT 82 115 TPR 2.
 REPEAT 116 149 TPR 3.
 ZN_FING 500 524 C3H1-type 1.
 ZN_FING 632 654 C3H1-type 2.
 ZN_FING 770 798 C3H1-type 3.
 ZN_FING 858 882 C2H2-type.
 ZN_FING 902 930 C3H1-type 4.
 MOTIF 264 272 LD motif; interaction with NSP3.
 MOD_RES 233 233 Phosphoserine.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Host-virus interaction; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; TPR repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 993 AA 
Protein Sequence
MERQKRKADI EKGLQFIQST LPLKQEEYEA FLLKLVQNLF AEGNDLFREK DYKQALVQYM 60
EGLNVADYAA SDQVALPREL LCKLHVNRAA CYFTMGLYEK ALEDSEKALG LDSESIRALF 120
RKARALNELG RHKEAYECSS RCSLALPHDE SVTQLGQELA QKLGLRVRKA YKRPQELETF 180
SLLSNGTAAG VADQGTSNGL GSIDDIETGN VPDTREQVEI GAPRDCYVDP RGSPALLPST 240
PTMPLFPHVL DLLAPLDSSR TLPSTDSLDD FSDGDVFGPE LDTLLDSLSL VQGGLSGSGV 300
PSELPQLIPV FPGGTPLLPP VVGGSIPVSS PLPPASFGLV MDPSKKLAAS VLDALDPPGP 360
TLDPLDLLPY SETRLDALDS FGSTRGSLDK PDSFMEETNS QDHRPPSGAQ KPAPSPEPCM 420
PNTALLIKNP LAATHEFKQA CQLCYPKTGP RAGDYTYREG LEHKCKRDIL LGRLRSSEDQ 480
TWKRIRPRPT KTSFVGSYYL CKDMINKQDC KYGDNCTFAY HQEEIDVWTE ERKGTLNRDL 540
LFDPLGGVKR GSLTIAKLLK EHQGIFTFLC EICFDSKPRI ISKGTKDSPS VCSNLAAKHS 600
FYNNKCLVHI VRSTSLKYSK IRQFQEHFQF DVCRHEVRYG CLREDSCHFA HSFIELKVWL 660
LQQYSGMTHE DIVQESKKYW QQMEAHAGKA SSSMGAPRTH GPSTFDLQMK FVCGQCWRNG 720
QVVEPDKDLK YCSAKARHCW TKERRVLLVM SKAKRKWVSV RPLPSIRNFP QQYDLCIHAQ 780
NGRKCQYVGN CSFAHSPEER DMWTFMKENK ILDMQQTYDM WLKKHNPGKP GEGTPISSRE 840
GEKQIQMPTD YADIMMGYHC WLCGKNSNSK KQWQQHIQSE KHKEKVFTSD SDASGWAFRF 900
PMGEFRLCDR LQKGKACPDG DKCRCAHGQE ELNEWLDRRE VLKQKLAKAR KDMLLCPRDD 960
DFGKYNFLLQ EDGDLAGATP EAPAAAATAT TGE 993 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0019048; P:virus-host interaction; IEA:UniProtKB-KW. 
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat.
 IPR015880; Znf_C2H2-like.
 IPR000571; Znf_CCCH. 
Pfam
 PF00642; zf-CCCH 
SMART
 SM00355; ZnF_C2H2
 SM00356; ZnF_C3H1 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION
 PS50103; ZF_C3H1
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS