CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022720
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable phospholipid-transporting ATPase 11C 
Protein Synonyms/Alias
 ATPase class VI type 11C 
Gene Name
 Atp11c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
677VWVLTGDKMETAKSTacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
  
Sequence Annotation
 ACT_SITE 409 409 4-aspartylphosphate intermediate (By
 METAL 816 816 Magnesium (By similarity).
 METAL 820 820 Magnesium (By similarity).
 MOD_RES 442 442 Phosphoserine (By similarity).
 MOD_RES 1105 1105 Phosphoserine.  
Keyword
 Alternative splicing; ATP-binding; Cell membrane; Coiled coil; Complete proteome; Endoplasmic reticulum; Hydrolase; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1129 AA 
Protein Sequence
MFRRTLNRLC AGEEKRVGTR TVFVGNHPIS GTEPYIAQRF CDNRIVSSKY TLWNFLPKNL 60
FEQFRRIANF YFLIIFLVQV TVDTPTSPVT SGLPLFFVIT VTAIKQGYED WLRHRADNEV 120
NKSAVYIIEN AKRVRKESEK IKVGDVVEVQ ANETFPCDLI LLSSCTTDGT CYVTTASLDG 180
ESNCKTHYAV RDTIALCTAE SIDNLRATIE CEQPQPDLYR FVGRISIYSN SIEAVARSLG 240
PENLLLKGAT LKNTKKIYGV AVYTGMETKM ALNYQGKSQK CSAVEKSINA FLIVYLFILL 300
TKAAVCTTLK YVWQSSPYND EPWYNQKTQK ERETFQVLKM FTDFLSFMVL FNFIIPVSMY 360
VTVEMQKFLG SFFISWDKDF FDEEINEGAL VNTSDLNEEL GQVDYVFTDK TGTLTENSME 420
FIECCIDGHK YKGTTQEVDG LSQTDGPLAY FDKADKNREA LFLRALCLCH TVEMKTNDDV 480
DGPVEGAGFT YISSSPDEIA LVKGAKRFGF TFLGNQNGYI RVENQRKEIE EYELLHTLNF 540
DSVRRRMSVI VRTQKGDILL FCKGADSSIF PRVHSHQIEL TKDHVERNAM DGYRTLCVAF 600
KEIPPDDFER INAQLVEAKM ALQDREEKLE KVFDEIETNM NLIGATAVED KLQDQAAETI 660
EALHAAGLKV WVLTGDKMET AKSTCYACRL FQTNTELLEL TTKTIEESER KEDRLHELLI 720
EYRKKLLHEF PKSTRSLKKA WTEHQEYGLI IDGSTLSLIL NSSQDCSSNN YKSIFLQICM 780
KCTAVLCCRM APLQKAQIVR MVKNLKGSPI TLSIGDGAND VSMILESHVG IGIKGKEGRQ 840
AARNSDYSVP KFKHLKKLLL VHGHLYYVRI AHLVQYFFYK NLCFILPQFL YQFFCGFSQQ 900
PLYDAAYLTM YNICFTSLPI LAYSLLEQHI NIDTLTADPR LYMKITGNAM LQLGPFLHWT 960
FLAAFEGTVF FFGTYFLFQT SSLEDNGKIY GNWTFGTIVF TVLVFTVTLK LALDTRFWTW 1020
INHFVIWGSL AFYVFFSFFW GGIIWPFLKQ QRMYFVFAQM LCSVSTWLAI ILLIFISLFP 1080
EILLIVVKNV RRRSARRNLS CRRASDSLSA RPSVRPLLLR TFSDESNIL 1129 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004012; F:phospholipid-translocating ATPase activity; IEA:EC. 
Interpro
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR006539; ATPase_P-typ_Plipid-transp.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00122; E1-E2_ATPase 
SMART
  
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS