CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029605
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hydroxyacid oxidase 1 
Protein Synonyms/Alias
 Hydroxyacid oxidase 1 (Mapped); Protein Hao1 
Gene Name
 Hao1 
Gene Synonyms/Alias
 Hao1_mapped; rCG_26596 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
21HARTVLQKSVYDYYKacetylation[1]
28KSVYDYYKSGANDQEacetylation[1]
48IRAFSRWKLYPRMLRacetylation[1]
249DDAQEAVKHGVDGILacetylation[1]
369KNPLAVSKI******acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 370 AA 
Protein Sequence
MLPRLVCISD YEQHARTVLQ KSVYDYYKSG ANDQETLADN IRAFSRWKLY PRMLRNVADI 60
DLSTSVLGQR VSMPICVGAT AMQCMAHVDG ELATVRACQT MGTGMMLSSW ATSSIEEVAE 120
AGPEALRWMQ LYIYKDREVS SQLVKRAEQM GYKAIFVTVD TPYLGNRFDD VRNRFKLPPQ 180
LRMKNFETND LAFSPKGNFG DNSGLAEYVA QAIDPSLSWD DIKWLRRLTS LPIVVKGILR 240
GDDAQEAVKH GVDGILVSNH GARQLDGVPA TIDALPEIVE AVEGKVEVFL DGGVRKGTDV 300
LKALALGARA VFVGRPIIWG LAFQGEKGVQ DVLEILKEEF RLAMALSGCQ NVKVIDKTLV 360
RKNPLAVSKI 370 
Gene Ontology
 GO:0005777; C:peroxisome; IEA:Compara.
 GO:0010181; F:FMN binding; IEA:Compara.
 GO:0008891; F:glycolate oxidase activity; IEA:Compara.
 GO:0001561; P:fatty acid alpha-oxidation; IEA:Compara.
 GO:0006979; P:response to oxidative stress; IEP:RGD. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR012133; Alpha-hydoxy_acid_DH_FMN.
 IPR000262; FMN-dep_DH.
 IPR008259; FMN_hydac_DH_AS. 
Pfam
 PF01070; FMN_dh 
SMART
  
PROSITE
 PS00557; FMN_HYDROXY_ACID_DH_1
 PS51349; FMN_HYDROXY_ACID_DH_2 
PRINTS