CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030012
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Peroxiredoxin-1 
Protein Synonyms/Alias
  
Gene Name
 Prdx1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
168QAFQFTDKHGEVCPAacetylation[1]
Reference
 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 176 AA 
Protein Sequence
MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS 60
DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK 120
ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAG 176 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005759; C:mitochondrial matrix; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005719; C:nuclear euchromatin; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005782; C:peroxisomal matrix; IEA:Compara.
 GO:0020037; F:heme binding; IEA:Compara.
 GO:0008379; F:thioredoxin peroxidase activity; IEA:Compara.
 GO:0008283; P:cell proliferation; IMP:MGI.
 GO:0034101; P:erythrocyte homeostasis; IMP:MGI.
 GO:0042744; P:hydrogen peroxide catabolic process; IEA:Compara.
 GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:MGI.
 GO:0042345; P:regulation of NF-kappaB import into nucleus; IMP:MGI.
 GO:0032872; P:regulation of stress-activated MAPK cascade; IMP:MGI.
 GO:0019430; P:removal of superoxide radicals; IMP:MGI. 
Interpro
 IPR000866; AhpC/TSA.
 IPR024706; Peroxiredoxin_AhpC-typ.
 IPR019479; Peroxiredoxin_C.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF10417; 1-cysPrx_C
 PF00578; AhpC-TSA 
SMART
  
PROSITE
 PS51352; THIOREDOXIN_2 
PRINTS