CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024930
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ligand of numb-protein X 2 
Protein Synonyms/Alias
  
Gene Name
 Lnx2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
422LTIARPGKPQPSNGSubiquitination[1]
487VAGGRGSKSGELPIFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 687 AA 
Protein Sequence
MGTTSDEMVP VEQASSTSSL DPLCFECGQQ HWARENHLYN YQGEVDDDLV CHICLQPLLQ 60
PLDTPCGHTF CHKCLRNFLQ EKDFCPLDRK RLHFKLCKKS SILVHKLLDK LLVLCPFSPV 120
CQDVMQRCDL EAHLKNRCPG ASHRRVDLER RKTSQTQTQI EGETGSTVID PPGTLPPETD 180
CSGTVPGERN LTPASLPVWT EEPGLDNPAF EESAAADSVQ QPLSLPEGEI TTIEIHRSNP 240
YIQLGISIVG GNETPLINIV IQEVYRDGVI ARDGRLLAGD QILQVNNYDI SNVSHNHARA 300
VLSQPCSTLQ LTVLRERRFG SRANSHADGS APRDEVFQVL LHKRDSTEQL GIKLVRRTDE 360
PGVFILDLLE GGLAAQDGRL NSNDRVLAIN GHHLKHGTPE LAAQIIQASG ERVNLTIARP 420
GKPQPSNGSR EAGAHSSSNH AQPPSHSRPG SHKDLTRCVT CQEKHITVKK EPHESLGMTV 480
AGGRGSKSGE LPIFVTSVPP HGCLARDGRI KRGDVLLNIN GIDLTNLSHS EAVAMLKASA 540
ASPAVILKAL EVQIAEEAAQ ATEEQPSAFS ENEYDASWSP SWVMWLGLPS ALHSCHDIVL 600
RRSYLGSWGF SIVGGYEENH TNQPFFIKTI VLGTPAYYDG RLKCGDMIVA VNGLSTVGMS 660
HSALVPMLKE QRNKVTLTVI CWPGSLV 687 
Gene Ontology
 GO:0030165; F:PDZ domain binding; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0051260; P:protein homooligomerization; IDA:MGI. 
Interpro
 IPR001478; PDZ.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00595; PDZ 
SMART
 SM00228; PDZ
 SM00184; RING 
PROSITE
 PS50106; PDZ
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS