CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039281
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Dock3 
Protein Synonyms/Alias
  
Gene Name
 Dock3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
54STKKPNVKGLFPANYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2030 AA 
Protein Sequence
VYKPTEDEDS FLVICSFRGS VPQGLVLEIG ETVQILEKCE GWYRGVSTKK PNVKGLFPAN 60
YIHLKKAIVS NRGQYETVVP LEDSIVTEVT ATLQEWASLW KQLYVKHKVD LFYKLRHVMN 120
ELIDLRRQLL SGHLTQDQVR EVKRHITVRL DWGNEHLGLD LVPRKDFEVV DSDQISVSDL 180
YKMHLSSRQS VQQSTSQVDT MRPRHGETCR MPVPHHFFFS LKSFTYNTIG EDSDVFFSLY 240
DMREGKQISE RFLVRLNKNG GPRNPEKIER MCALFTDLSS KDMKRDLYIV AHVIRIGRML 300
LNDSKKGPAH LHYRRPYGCA VLSILDVLQS LTELKEEKDF VLKVYTCNNE SEWTQIHENI 360
IRKSSTKYSA PSASHGLIIS LQLFRGDMEQ IRRENPMIFN RGLAITRKLG FPDVIMPGDI 420
RNDLYLTLEK GDFERGGKSV QKNIEVTMYV LYADGEILKD CISLGSGEPN RSSYHSFVLY 480
HSNSPRWGEI IKLPIPIDRF RGSHLRFEFR HCSTKDKGEK KLFGFSFSPL MRDDGTTLSD 540
DIHELYVYKC DENSTFNNHA LYLGLPCCKE DYNGCPNIPS SLIFQRSTKE SFFISTQLSS 600
TKLTQNVDLL ALLKWKAFPD RIMDILGRLR HVSGEEIVKF LQDILDTLFV ILDDNTEKYG 660
LLVFQSLVFI INLLRDIKYF HFRPVMDTYI QKHFAGALAY KELIRCLKWY MDCSAELIRQ 720
DHIQEAMRAL EYLFKFIVQS RILYSRATCG MEEEQFRSSI QELFQSIRFV LSLDSRNSET 780
LLFTQAALLN SFPTIFDELL QMFTVQEVAE FVRGTLGSMP STVHIGQSMD VVKLQSIART 840
VDSRLFSFSE SRRILLPVVL HHIHLHLRQQ KELLICSGIL GSIFSIVKTS SLEADVMEEV 900
EMMVESLLDV LLQTLLTIMS KSHAQEAVRG QRCPQCTAEI TGEYVSCLLS LLRQMCDTHY 960
QHLLDNFQSK DELKEFLLKI FCVFRNLMKM SVFPRDWMVM RLLTSNIIVT TVQYLSSALH 1020
KNFTETDFDF KVWNSYFSLA VLFINQPSLQ LEIITSAKRK KILDKYGDMR VMMAYELFSM 1080
WQNLGEHKIH FIPGMIGPFL GVTLVPQPEV RNIMIPIFHD MMDWEQRKNG NFKQVESELI 1140
DKLDSMVSEG KGDESYRELF SLLTQLFGPY PSLLEKVEQE TWRETGISFV TSVTRLMERL 1200
LDYRDCMKGE ETENKKVGCT VNLMNFYKSE INKEEMYIRY IHKLCDMHLQ AENYTEAAFT 1260
LLLYCELLQW EDRPLREFLH YPSQTEWQRK EGLCRKIIHY FNKGKSWEFG IPLCRELACQ 1320
YESLYDYQSL SWIRKMEASY YDNIIEQQRL EPEFFRVGFY GRKFPFFLRN KEYVCRGHDY 1380
ERLEAFQQRM LSEFPQAVAM QHPNHPDDAI LQCDAQYLQI YAVTPIPDYV DVLQMDRVPD 1440
RVKSFYRVNN VRKFRYDRPF HKGPKDKDNE FKSLWIERTT LTLTHSLPGI SRWFEVERRE 1500
LVEVSPLENA IQVVENKNQE LRALISQYQH KQVHGNINLL SMCLNGVIDA AVNGGIARYQ 1560
EAFFDKDYIT KHPGDAEKIS QLKELMQEQV HVLGVGLAVH EKFVHPEMRP LHKKLIDQFQ 1620
MMRASLYHEF PCLDKLSPAC SGTSTPRGNV LASHSPMSPE NIKMSHRHSP MNLMGTGRHS 1680
SSSLSSHASS EAGNMMMMGD NSMGETPEDL YHHMQLAYHN PRYQGSVTNV SVLSSSQASP 1740
SSSSLSSTHS APSQMITSAP SSTRGSPSLP DKYRHAREMM LLLPTHRDRP SSAMYPAAIL 1800
ENGQPANFQR ALFQQVVGAC KPCSDPNLSM AEKGHYSLHF DAFHHPLGDT PPALPARTLR 1860
KSPLHPIPAS PTSPQSGLDG SNSTLSGSAS SGVSSLSESN FGHSSEAPPR TDTMDSMPSQ 1920
AWNGDEDLEP PYLPVHYSLS ESAVLDSIKS QPCRSHSAPG CVIPQDPMDP PALPPKPYHP 1980
RLPALEHDEG VLLREEAERP RGLHRKASLP PGSAKEEQAR MAWEHGRGEQ 2030 
Gene Ontology
 GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027007; DHR-1_domain.
 IPR027357; DHR-2.
 IPR026791; DOCK.
 IPR026800; DOCK_B.
 IPR010703; DOCK_C.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF06920; Ded_cyto
 PF14429; DOCK-C2
 PF07653; SH3_2 
SMART
 SM00326; SH3 
PROSITE
 PS51650; DHR_1
 PS51651; DHR_2
 PS50002; SH3 
PRINTS