CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024255
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Meromycolate extension acyl carrier protein 
Protein Synonyms/Alias
 ACP 
Gene Name
 acpM 
Gene Synonyms/Alias
 MSMEG_4326; MSMEI_4226 
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
58TEDKYGVKIPDEDLApupylation[1]
79DVVAYIQKLEEENPEpupylation[1, 2]
Reference
 [1] Proteome-wide identification of mycobacterial pupylation targets.
 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH.
 Mol Syst Biol. 2010 Jul 13;6:386. [PMID: 20631680]
 [2] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657
Functional Description
 Acyl carrier protein involved in meromycolate extension (By similarity). 
Sequence Annotation
 MOD_RES 41 41 O-(pantetheine 4'-phosphoryl)serine (By
 CROSSLNK 79 79 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Cytoplasm; Fatty acid biosynthesis; Fatty acid metabolism; Isopeptide bond; Lipid biosynthesis; Lipid metabolism; Phosphopantetheine; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 99 AA 
Protein Sequence
MAATQEEIIA GLAEIIEEVT GIEPSEVTPE KSFVDDLDID SLSMVEIAVQ TEDKYGVKIP 60
DEDLAGLRTV GDVVAYIQKL EEENPEAAAA LREKFAADQ 99 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000036; F:ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process; IEA:HAMAP. 
Interpro
 IPR003231; Acyl_carrier.
 IPR009081; Acyl_carrier_prot-like. 
Pfam
 PF00550; PP-binding 
SMART
  
PROSITE
 PS50075; ACP_DOMAIN
 PS00012; PHOSPHOPANTETHEINE 
PRINTS