Tag | Content |
---|
CPLM ID | CPLM-039755 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nik-related protein kinase |
Protein Synonyms/Alias | |
Gene Name | NRK |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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819 | SLLEQAQKPIDIRQR | methylation | [1] |
|
Reference | [1] A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation. Moore KE, Carlson SM, Camp ND, Cheung P, James RG, Chua KF, Wolf-Yadlin A, Gozani O. Mol Cell. 2013 May 9;50(3):444-56. [ PMID: 23583077] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1583 AA |
Protein Sequence | MAGPGGWRDR EVTDLGHLPD PTGIFSLDKT IGLGTYGRIY LGLHEKTGAF TAVKVMNARK 60 TPLPEIGRRV RVNKYQKSVG WRYSDEEEDL RTELNLLRKY SFHKNIVSFY GAFFKLSPPG 120 QRHQLWMVME LCAAGSVTDV VRMTSNQSLK EDWIAYICRE ILQGLAHLHA HRVIHRDIKG 180 QNVLLTHNAE VKLVDFGVSA QVSRTNGRRN SFIGTPYWMA PEVIDCDEDP RRSYDYRSDV 240 WSVGITAIEM AEGAPPLCNL QPLEALFVIL RESAPTVKSS GWSRKFHNFM EKCTIKNFLF 300 RPTSANMLQH PFVRDIKNER HVVESLTRHL TGIIKKRQKK KGIPLIFERE EAIKEQYTVR 360 RFRGPSCTHE LLRLPTSSRC RPLRVLHGEP SQPRWLPDRE EPQVQALQQL QGAARVFMPL 420 QALDSAPKPL KGQAQAPQRL QGAARVFMPL QAQVKAKASK PLQMQIKAPP RLRRAARVLM 480 PLQAQVRAPR LLQVQSQVSK KQQAQTQTSE PQDLDQVPEE FQGQDQVPEQ QRQGQAPEQQ 540 QRHNQVPEQE LEQNQAPEQP EVQEQAAEPA QAETEAEEPE SLRVNAQVFL PLLSQDHHVL 600 LPLHLDTQVL IPVEGQTEGS PQAQAWTLEP PQAIGSVQAL IEGLSRDLLR APNSNNSKPL 660 GPLQTLMENL SSNRFYSQPE QAREKKSKVS TLRQALAKRL SPKRFRAKSS WRPEKLELSD 720 LEARRQRRQR RWEDIFNQHE EELRQVDKDK EDESSDNDEV FHSIQAEVQI EPLKPYISNP 780 KKIEVQERSP SVPNNQDHAH HVKFSSSVPQ RSLLEQAQKP IDIRQRSSQN RQNWLAASES 840 SSEEESPVTG RRSQSSPPYS TIDQKLLVDI HVPDGFKVGK ISPPVYLTNE WVGYNALSEI 900 FRNDWLTPAP VIQPPEEDGD YVELYDASAD TDGDDDDESN DTFEDTYDHA NGNDDLDNQV 960 DQANDVCKDH DDDNNKFVDD VNNNYYEAPS CPRASYGRDG SCKQDGYDGS RGKEEAYRGY 1020 GSHTANRSHG GSAASEDNAA IGDQEEHAAN IGSERRGSEG DGGKGVVRTS EESGALGLNG 1080 EENCSETDGP GLKRPASQDF EYLQEEPGGG NEASNAIDSG AAPSAPDHES DNKDISESST 1140 QSDFSANHSS PSKGSGMSAD ANFASAILYA GFVEVPEESP KQPSEVNVNP LYVSPACKKP 1200 LIHMYEKEFT SEICCGSLWG VNLLLGTRSN LYLMDRSGKA DITKLIRRRP FRQIQVLEPL 1260 NLLITISGHK NRLRVYHLTW LRNKILNNDP ESKRRQEEML KTEEACKAID KLTGCEHFSV 1320 LQHEETTYIA IALKSSIHLY AWAPKSFDES TAIKVCIDQS ADSEGDYMSY QAYIRILAKI 1380 QAADPVNRFK RPDELLHLLK LKVFPTLDHK PVTVDLAIGS EKRLKIFFSS ADGYHLIDAE 1440 SEVMSDVTLP KNPLEIIIPQ NIIILPDCLG IGMMLTFNAE ALSVEANEQL FKKILEMWKD 1500 IPSSIAFECT QRTTGWGQKA IEVRSLQSRV LESELKRRSI KKLRFLCTRG DKLFFTSTLR 1560 NHHSRVYFMT LGKLEELQSN YDV 1583 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. GO:0005083; F:small GTPase regulator activity; IEA:InterPro. GO:0007256; P:activation of JNKK activity; IEA:Compara. GO:0008285; P:negative regulation of cell proliferation; IEA:Compara. GO:0007567; P:parturition; IEA:Compara. GO:0060721; P:regulation of spongiotrophoblast cell proliferation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |