CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase SHPRH 
Protein Synonyms/Alias
  
Gene Name
 SHPRH 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
59SKVVSFSKPIEKEETacetylation[1]
400HYFGGKLKKTEIQNIubiquitination[2]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 449 AA 
Protein Sequence
WNMHEDRRNE PIIISDDDEQ PCPGSDTSSA HYIILSDSLK EEVAHRDKKR CSKVVSFSKP 60
IEKEETVGIF SPLSVKLNIV ISPYHFDNSW KAFLGELTLQ LLPAQSLIEN FSERSITLMS 120
SESSNQFLIY VHSKGEDVEK QKKEPMSICD KGILVESSFS GEMLEDLGWL QKKRRIKLYQ 180
KPEGNHIIKV GIYLLEAGLA KLDFLSDANS RMKKFNQLMK KVMEKLHNSI IPDVLEEDED 240
DPESEPEGQD IDELYHFVKQ THQQETQSIQ VDVQHPALIP VLRPYQREAV NWMLQQECFR 300
SSPATESALH FLWREIVTSE GLKLYYNPYT GCIIREYPNS GPQLLGGILA DEMGLGKTVE 360
VLALILTHTR QDVKQDALTL PEGKVVNYFI PSHYFGGKLK KTEIQNIEFE PKEKVQCPPY 420
PFTFSYTCDD TDSCERNEWK KRSVHPFHL 449 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N. 
Pfam
 PF00176; SNF2_N 
SMART
  
PROSITE
  
PRINTS