UniProt Accession

 LEG9_MOUSE; O08573; O08572; Q3UKE5 

Genbank Protein ID

 U55061; U55060; AK146044; AL592551; AL592185; AL592185; AL592551; CH466556 

Genbank Nucleotide ID

 AAB51190.1; AAB51189.1; BAE26856.1; CAI24050.1; CAI24050.1; CAI25276.1; CAI25276.1; EDL15600.1 

Protein Name

 Galectin-9 

Protein Synonyms/Alias

 Gal-9 

Gene Name

 Lgals9 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
76	GYVVCNTKQNGQWGP	ubiquitination	[1]
87	QWGPEERKMQMPFQK	ubiquitination	[1]
110	LVQRSEFKVMVNKKF	ubiquitination	[1]
116	FKVMVNKKFFVQYQH	ubiquitination	[1]
301	CEYYHRLKNLQDINT	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Binds galactosides. May play a role in thymocyte- epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity). 

Sequence Annotation

 DOMAIN 17 147 Galectin 1.
 DOMAIN 225 353 Galectin 2.
 REGION 81 87 Beta-galactoside binding 1.
 REGION 285 291 Beta-galactoside binding 2 (By
 BINDING 47 47 Beta-galactoside 1.
 BINDING 60 60 Beta-galactoside 1.
 BINDING 64 64 Beta-galactoside 1.
 BINDING 74 74 Beta-galactoside 1.
 BINDING 265 265 Beta-galactoside 2 (By similarity).
 BINDING 269 269 Beta-galactoside 2 (By similarity).
 BINDING 279 279 Beta-galactoside 2 (By similarity).  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Lectin; Reference proteome; Repeat; Secreted. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 353 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0030246; F:carbohydrate binding; ISS:UniProtKB.
 GO:0016936; F:galactoside binding; ISA:MGI.
 GO:0007157; P:heterophilic cell-cell adhesion; ISA:MGI. 

Interpro

 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR001079; Galectin_CRD. 

Pfam

 PF00337; Gal-bind_lectin 

SMART

 SM00908; Gal-bind_lectin
 SM00276; GLECT 

PROSITE

 PS51304; GALECTIN 

PRINTS