UniProt Accession

 F8WEF0_HUMAN; F8WEF0 

Genbank Protein ID

 AC073284 

Genbank Nucleotide ID

  

Protein Name

 Phosphoribosylaminoimidazolecarboxamide formyltransferase 

Protein Synonyms/Alias

  

Gene Name

 ATIC 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
14	ALFSVSDKTGLVEFA	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 84 AA 

Protein Sequence

Gene Ontology

 GO:0003937; F:IMP cyclohydrolase activity; IEA:InterPro.
 GO:0004643; F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity; IEA:InterPro.
 GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro. 

Interpro

 IPR002695; AICARFT_IMPCHas.
 IPR011607; MGS-like_dom. 

Pfam

 PF02142; MGS 

SMART

 SM00851; MGS 

PROSITE

  

PRINTS