CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021982
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translocase of inner mitochondrial membrane domain-containing protein 1 
Protein Synonyms/Alias
 Protein M5-14 
Gene Name
 TIMMDC1 
Gene Synonyms/Alias
 C3orf1; UNQ247/PRO284 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
237ELKLEEWKGRLQVTEubiquitination[1]
264DEPENDAKKIEALLNubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 285 AA 
Protein Sequence
MEVPPPAPRS FLCRALCLFP RVFAAEAVTA DSEVLEERQK RLPYVPEPYY PESGWDRLRE 60
LFGKDEQQRI SKDLANICKT AATAGIIGWV YGGIPAFIHA KQQYIEQSQA EIYHNRFDAV 120
QSAHRAATRG FIRYGWRWGW RTAVFVTIFN TVNTSLNVYR NKDALSHFVI AGAVTGSLFR 180
INVGLRGLVA GGIIGALLGT PVGGLLMAFQ KYSGETVQER KQKDRKALHE LKLEEWKGRL 240
QVTEHLPEKI ESSLQEDEPE NDAKKIEALL NLPRNPSVID KQDKD 285 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:LIFEdb. 
Interpro
 IPR003397; Tim17/Tim22/Tim23/PMP24. 
Pfam
 PF02466; Tim17 
SMART
  
PROSITE
  
PRINTS