CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041991
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DAN domain family member 5 
Protein Synonyms/Alias
 Sp1 transcription factor, isoform CRA_b 
Gene Name
 SP1 
Gene Synonyms/Alias
 hCG_1787889 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
603ACTCPYCKDSEGRGSubiquitination[1, 2]
678RTHTGEKKFACPECPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 778 AA 
Protein Sequence
MDEMTAVVKI EKGVGGNNGG NGNGGGAFSQ ARSSSTGSSS STGGGGQESQ PSPLALLAAT 60
CSRIESPNEN SNNSQGPSQS GGTGELDLTA TQLSQGANGW QIISSSSGAT PTSKEQSGSS 120
TNGSNGSESS KNRTVSGGQY VVAAAPNLQN QQVLTGLPGV MPNIQYQVIP QFQTVDGQQL 180
QFAATGAQVQ QDGSGQIQII PGANQQIITN RGSGGNIIAA MPNLLQQAVP LQGLANNVLS 240
GQTQYVTNVP VALNGNITLL PVNSVSAATL TPSSQAVTIS SSGSQESGSQ PVTSGTTISS 300
ASLVSSQASS SSFFTNANSY STTTTTSNMG IMNFTTSGSS GTNSQGQTPQ RVSGLQGSDA 360
LNIQQNQTSG GSLQAGQQKE GEQNQQTQQQ QILIQPQLVQ GGQALQALQA APLSGQTFTT 420
QAISQETLQN LQLQAVPNSG PIIIRTPTVG PNGQVSWQTL QLQNLQVQNP QAQTITLAPM 480
QGVSLGQTSS SNTTLTPIAS AASIPAGTVT VNAAQLSSMP GLQTINLSAL GTSGIQVHPI 540
QGLPLAIANA PGDHGAQLGL HGAGGDGIHD DTAGGEEGEN SPDAQPQAGR RTRREACTCP 600
YCKDSEGRGS GDPGKKKQHI CHIQGCGKVY GKTSHLRAHL RWHTGERPFM CTWSYCGKRF 660
TRSDELQRHK RTHTGEKKFA CPECPKRFMR SDHLSKHIKT HQNKKGGPGV ALSVGTLPLD 720
SGAGSEGSGT ATPSALITTN MVAMEAICPE GIARLANSGI NVMQVADLQS INISGNGF 778 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0032993; C:protein-DNA complex; IEA:Compara.
 GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Compara.
 GO:0003690; F:double-stranded DNA binding; IEA:Compara.
 GO:0035326; F:enhancer binding; IEA:Compara.
 GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Compara.
 GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0060216; P:definitive hemopoiesis; IEA:Compara.
 GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Compara.
 GO:0001892; P:embryonic placenta development; IEA:Compara.
 GO:0060136; P:embryonic process involved in female pregnancy; IEA:Compara.
 GO:0048706; P:embryonic skeletal system development; IEA:Compara.
 GO:0043353; P:enucleate erythrocyte differentiation; IEA:Compara.
 GO:0001889; P:liver development; IEA:Compara.
 GO:0030324; P:lung development; IEA:Compara.
 GO:0030219; P:megakaryocyte differentiation; IEA:Compara.
 GO:0001503; P:ossification; IEA:Compara.
 GO:0001829; P:trophectodermal cell differentiation; IEA:Compara. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS