CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034255
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glyceraldehyde-3-phosphate dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 Gm5069 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
61SKFNGTVKAENGKLVacetylation[1]
221GAAKAVGKVIPELNGubiquitination[2]
Reference
 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 337 AA 
Protein Sequence
MVKAGVNGFG HIGRLVTRVA ICSLHGKVEI VAINDPFIDL DYMVYMFQYD STHSKFNGTV 60
KAENGKLVIN GKPITIFQER DCPPPNIKWD EASAEYVVES TGVFTTMEKA GAHLKGGAKR 120
VIISVRSADA PMFVMGVNHE KYDNSLKIVS NASCTTNCLA PLAKVIHDNF GIVEGLMTTV 180
HAITATQKTV DGPSGKLWRD GRGATQNIIP ASTGAAKAVG KVIPELNGKL TGMAFRVPNP 240
NVSIVDLTCR LEKPAKYDDI KKVVKQASEG PQKGILGYTE DQVASCDFNS NSHSSTFDAG 300
AGIALNDNFV KLISWYDNEY GYSNRVVDLM AYMASKE 337 
Gene Ontology
 GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; IEA:EC.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006006; P:glucose metabolic process; IEA:InterPro. 
Interpro
 IPR020831; GlycerAld/Erythrose_P_DH.
 IPR020830; GlycerAld_3-P_DH_AS.
 IPR020829; GlycerAld_3-P_DH_cat.
 IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
 IPR006424; Glyceraldehyde-3-P_DH_1.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02800; Gp_dh_C
 PF00044; Gp_dh_N 
SMART
 SM00846; Gp_dh_N 
PROSITE
 PS00071; GAPDH 
PRINTS
 PR00078; G3PDHDRGNASE.