UniProt Accession

 LSM7_MOUSE; Q9CQQ8 

Genbank Protein ID

 AK013355; BC027511; BC081444; AK003062; AK007462; AK012446 

Genbank Nucleotide ID

 BAB28806.1; AAH27511.1; AAH81444.1; BAB22540.1; BAB25051.1; BAB28245.1 

Protein Name

 U6 snRNA-associated Sm-like protein LSm7 

Protein Synonyms/Alias

  

Gene Name

 Lsm7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
17	ESILDLSKYIDKTIR	acetylation	[1]
17	ESILDLSKYIDKTIR	ubiquitination	[2]
21	DLSKYIDKTIRVKFQ	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Ribonucleoprotein; RNA-binding; Spliceosome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 103 AA 

Protein Sequence

Gene Ontology

 GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 

Interpro

 IPR010920; LSM_dom.
 IPR001163; Ribonucl_LSM.
 IPR006649; Ribonucl_LSM_euk/arc.
 IPR017132; U6_snRNA_Lsm7. 

Pfam

 PF01423; LSM 

SMART

 SM00651; Sm 

PROSITE

  

PRINTS