UniProt Accession

 TPRKB_HUMAN; Q9Y3C4; D6W5H6; Q8IWR6; Q8IWR7; Q9H3K4 

Genbank Protein ID

 AY157986; AY157987; AF060921; AF151879; CH471053; CH471053; BC029492 

Genbank Nucleotide ID

 AAN76356.1; AAN76357.1; AAG43133.1; AAD34116.1; EAW99720.1; EAW99722.1; AAH29492.1 

Protein Name

 TP53RK-binding protein 

Protein Synonyms/Alias

 PRPK-binding protein 

Gene Name

 TPRKB 

Gene Synonyms/Alias

 CGI-121; My019 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
21	RVTLLLFKDVKNAGD	ubiquitination	[1, 2]
24	LLLFKDVKNAGDLRR	ubiquitination	[1]
105	NKAVHLYKLGKMKTR	ubiquitination	[1]
189	TEVKKIYKLSSQEES	ubiquitination	[1]
211	IICRMSTKDVL****	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 MOD_RES 132 132 Phosphoserine.  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 175 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0030163; P:protein catabolic process; NAS:UniProtKB. 

Interpro

 IPR013926; CGI121/TPRKB. 

Pfam

 PF08617; CGI-121 

SMART

  

PROSITE

  

PRINTS