CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037667
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Coiled-coil domain-containing protein 15 
Protein Synonyms/Alias
  
Gene Name
 CCDC15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
24PLALNPLKSKDVLAVubiquitination[1]
26ALNPLKSKDVLAVLAubiquitination[1]
112KSYERAQKEGSIAMQubiquitination[1]
128SATHLTSKRTSVFPNubiquitination[1]
188RHRLASFKTVIKKKGubiquitination[1]
292QAIHSEDKNKPFSRVubiquitination[1]
294IHSEDKNKPFSRVQKubiquitination[1]
305RVQKVKFKNPLFVLMubiquitination[1]
385EPEGQPIKTETQGIMubiquitination[1]
422TNQALLTKNQDVLLKubiquitination[1]
429KNQDVLLKDHCVLPKubiquitination[1]
436KDHCVLPKDQSILLKubiquitination[1]
443KDQSILLKYQDQDFLubiquitination[1, 2]
459RDQHVLHKDQDILPKubiquitination[1]
466KDQDILPKYQDQNFLubiquitination[1]
475QDQNFLPKDQNFLSRubiquitination[1, 3]
535QGQDFLPKDQDFLSRubiquitination[1]
556KDWNILPKCQDQDFLubiquitination[1]
572RDQGVLPKDQNILPIubiquitination[1]
595RDQGYLPKDQNILPIubiquitination[1]
625NDQNILPKCQDQDFLubiquitination[1]
703YHQYVVPKIQDQDSPubiquitination[1]
725KLPSSFEKWEIARGNubiquitination[1]
834EDPYSGEKLSEILAQubiquitination[1]
848QLQLQEIKGTREKQQubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 962 AA 
Protein Sequence
MLGSMARKKP RNTSRLPLAL NPLKSKDVLA VLAERNEAIV PVGAWVEPAS PGSSEIPAYT 60
SAYLIEEELK EQLRKKQEAL KHFQKQVKYR VNQQIRLRKK QQLQKSYERA QKEGSIAMQS 120
SATHLTSKRT SVFPNNLNVA IGSSRLPPSL MPGDGIEDEE NQNELFQQQA QALSETMKQA 180
RHRLASFKTV IKKKGSVFPD DGRKSFLTRE EVLSRKPAST GINTGIRGEL PIKVHQGLLA 240
AVPYQNYMEN QELDYEEPDY EESSSLVTDE KGKEDLFGRG QQDQQAIHSE DKNKPFSRVQ 300
KVKFKNPLFV LMEEEEQKQL HFEGLQDILP EAQDYFLEAQ GDLLETQGDL TGIQSVKPDT 360
QAVEMKVQVT EPEGQAIEPE GQPIKTETQG IMLKAQSIEL EEGSIVLKTQ DFLPTNQALL 420
TKNQDVLLKD HCVLPKDQSI LLKYQDQDFL PRDQHVLHKD QDILPKYQDQ NFLPKDQNFL 480
SRDQHVLPKD QDILPKYQDQ NFLPKDQNFL SRDQHVLPKD QNILPKYQGQ DFLPKDQDFL 540
SRDQHVLPKD WNILPKCQDQ DFLPRDQGVL PKDQNILPIC QDQDFLPRDQ GYLPKDQNIL 600
PICQDRDFLP RDLHVLSNDQ NILPKCQDQD FLPKYQKVHF KEPYSDMTDE KGREDFSLAD 660
YQCLPPKSQD QDDIKNQQPA SFMREERVRE ELPLDYHQYV VPKIQDQDSP REQNKHIKLP 720
SSFEKWEIAR GNTPGVPLAY DRYQSGLSTE FQAPLAFQSD VDKEEDKKER QKQYLRHRRL 780
FMDIEREQVK EQQRQKEQKK KIEKIKKKRE QECYAAEQRI LRMNFHEDPY SGEKLSEILA 840
QLQLQEIKGT REKQQREKEY LSSLCLIILY LYRYVEALRA QIQEKMQLYN ITLPPLCCCG 900
PDFWDAHPDT CANNCIFYKN HRAYTRALHS FINSCDVPGG NSTLRVAIHN FASAHRRTLK 960
NL 962 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS