UniProt Accession

 PSME2_RAT; Q63798; Q4QR96 

Genbank Protein ID

 D45250; BC058486; BC097331 

Genbank Nucleotide ID

 BAA08207.1; AAH58486.1; AAH97331.1 

Protein Name

 Proteasome activator complex subunit 2 

Protein Synonyms/Alias

 11S regulator complex subunit beta; REG-beta; Activator of multicatalytic protease subunit 2; Proteasome activator 28 subunit beta; PA28b; PA28beta 

Gene Name

 Psme2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
15	RLSGEARKQVDAFRQ	acetylation	[1]
155	RVNAVKTKVEAFQTA	acetylation	[1]
179	DAVAKASKDTHVMDY	acetylation	[1]
234	VNPKGEEKPSMY***	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 10 10 Phosphoserine (By similarity).  

Keyword

 Acetylation; Complete proteome; Phosphoprotein; Proteasome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 238 AA 

Protein Sequence

Gene Ontology

 GO:0008537; C:proteasome activator complex; IEA:InterPro. 

Interpro

 IPR003185; Proteasome_activ_REG_asu.
 IPR009077; Proteasome_activ_REG_asu/bsu.
 IPR003186; Proteasome_activ_REG_bsu. 

Pfam

 PF02251; PA28_alpha
 PF02252; PA28_beta 

SMART

  

PROSITE

  

PRINTS