CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045742
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enhancer of zeste, isoform C 
Protein Synonyms/Alias
  
Gene Name
 E(z) 
Gene Synonyms/Alias
 Dmel_CG6502 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
20RVKSEYIKIRQQKRYacetylation[1]
732HRIGIFAKRAIQPGEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Methyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 765 AA 
Protein Sequence
MNSTKVPPEW KRRVKSEYIK IRQQKRYKRA DEIKEAWIRN WDEHNHNVQD LYCESKVWQA 60
KPYDPPHVDC VKRAEVTSYN GIPSGPQKVP ICVINAVTPI PTMYTWAPTQ QNFMVEDETV 120
LHNIPYMGDE VLDKDGKFIE ELIKNYDGKV HGDKDPSFMD DAIFVELVHA LMRSYSKELE 180
EAAPGTATAI KTETLAKSKQ GEDDGVVDVD ADGESPMKLE KTDSKGDLTE VEKKETEEPL 240
ETEDADVKPD VEEVKDKLPF PAPIIFQAIS ANFPDKGTAQ ELKEKYIELT EHQDPERPQE 300
CTPNIDGIKA ESVSRERTMH SFHTLFCRRC FKYDCFLHRH HVQGLQGHAG PNLQKRRYPE 360
LKPFAEPCSN SCYMLIDGMK EKLAADSKTP PIDSCNEASS EDSNDSNSQF SNKDFNHENS 420
KDNGLTVNSA AVAEINSIMA GMMNITSTQC VWTGADQALY RVLHKVYLKN YCAIAHNMLT 480
KTCRQVYEFA QKEDAEFSFE DLRQDFTPPR KKKKKQRLWS LHCRKIQLKK DSSSNHVYNY 540
TPCDHPGHPC DMNCSCIQTQ NFCEKFCNCS SDCQNRFPGC RCKAQCNTKQ CPCYLAVREC 600
DPDLCQACGA DQFKLTKITC KNVCVQRGLH KHLLMAPSDI AGWGIFLKEG AQKNEFISEY 660
CGEIISQDEA DRRGKVYDKY MCSFLFNLNN DFVVDATRKG NKIRFANHSI NPNCYAKVMM 720
VTGDHRIGIF AKRAIQPGEE LFFDYRYGPT EQLKFVGIER EMEIV 765 
Gene Ontology
 GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
 GO:0034968; P:histone lysine methylation; IEA:GOC. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS