| Tag | Content |
|---|
| CPLM ID | CPLM-015337 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Docking protein 6 |
Protein Synonyms/Alias | Downstream of tyrosine kinase 6 |
Gene Name | DOK6 |
Gene Synonyms/Alias | DOK5L |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 58 | AYFRNFHKVTELHNI | methylation | [1] |
|
Reference | [1] Large-scale global identification of protein lysine methylation in vivo. Cao XJ, Arnaudo AM, Garcia BA. Epigenetics. 2013 May 1;8(5):477-85. [ PMID: 23644510] |
Functional Description | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret- mediated neurite growth. May have a role in brain development and/or maintenance. |
Sequence Annotation | DOMAIN 8 112 PH.
DOMAIN 132 237 IRS-type PTB.
MOTIF 263 273 DKFBH motif. |
Keyword | Complete proteome; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 331 AA |
Protein Sequence | MASNFNDIVK QGYVKIRSRK LGIFRRCWLV FKKASSKGPR RLEKFPDEKA AYFRNFHKVT 60
ELHNIKNITR LPRETKKHAV AIIFHDETSK TFACESELEA EEWCKHLCME CLGTRLNDIS 120
LGEPDLLAAG VQREQNERFN VYLMPTPNLD IYGECTMQIT HENIYLWDIH NAKVKLVMWP 180
LSSLRRYGRD STWFTFESGR MCDTGEGLFT FQTREGEMIY QKVHSATLAI AEQHERLMLE 240
MEQKARLQTS LTEPMTLSKS ISLPRSAYWH HITRQNSVGE IYSLQGHGFG SSKMSRAQTF 300
PSYAPEQSEE AQQPLSRSSS YGFSYSSSLI Q 331 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |