CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001368
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AP-1 complex subunit gamma-like 2 
Protein Synonyms/Alias
 Gamma2-adaptin; G2ad 
Gene Name
 Ap1g2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
145DLAPEVEKLLLQPSPubiquitination[1]
573EYNTLFQKYDHMRAAubiquitination[1]
584MRAAILEKMPLVERGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May function in protein sorting in late endosomes or multivesucular bodies (MVBs). 
Sequence Annotation
 DOMAIN 671 786 GAE.  
Keyword
 Complete proteome; Cytoplasmic vesicle; Endosome; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 791 AA 
Protein Sequence
MVVHSLRLQD LIEEIRGAKT QAQEREVIQK ECAQIRASFR DGDPLQRHRQ LAKLLYVHML 60
GYPAHFGQME CLKLIASPRF TDKRVGYLGA MLLLDERHDS HLLITNSIKN DLSQGNQPVQ 120
GLALCTLSTM GSAEMCRDLA PEVEKLLLQP SPYVRKKAIL TAVHMIRKDP ELSGIFLPPC 180
TKLLRERHHG IQLGTVTLIT ELCERNPAAL RHFRKVVPQL VQILRTLVTT GYSTEHSISG 240
VSDPFLQVQI LRLLRILGRN HEESSETMND LLAQVATNTD TSRNAGNAVL LETVLTIMAI 300
HSAAGLRVLA VNILGRFLLN NDKNIRYVAL TSLLQLVQSD HSAVQRHRST VVECLQETDA 360
SLSRRALELS LALVNSSNVR AMMQELQAFL ESCPPDLRAD CASGILLAAE RFAPSKRWHI 420
DTILHVLTTA GAHVRDDAVA NLTQLIGEAE ELHTYSVRRL YSALAEDISQ QPLVQVAAWC 480
IGEYGDLLLE GNCEETEPFQ VEEEDVLALL EKVLQSHMSL PATRGYAITA LMKLSTRLRG 540
DNNRIRQVVS IYGSCVDLEL QQRAVEYNTL FQKYDHMRAA ILEKMPLVER GDPHVKEGGK 600
EKQTEAQPLE VTAPAPTEPQ ATKLLDLLDL LGDTSEPLSS GHAQHLPPQT PSPGEALIHL 660
LDLPCTPPPP APIPSVRVFE REGLQLDLSF MRPLETPALL LVTATTTNSS KEDVTHFVCQ 720
AAVPKSFQLQ LQAPSGNTIP AQGGLPITQV FRILNPNQAP LRLKLRLTYN HSGQPVQEIF 780
EVDNLPVETW Q 791 
Gene Ontology
 GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
 GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.
 GO:0016020; C:membrane; ISS:UniProtKB.
 GO:0005802; C:trans-Golgi network; TAS:MGI.
 GO:0030133; C:transport vesicle; ISS:UniProtKB.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; TAS:MGI.
 GO:0016192; P:vesicle-mediated transport; TAS:MGI. 
Interpro
 IPR017107; AP1_complex_gsu.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR002553; Clathrin/coatomer_adapt-like_N.
 IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
 IPR008153; Clathrin_g-adaptin_app.
 IPR013041; Coatomer/clathrin_app_Ig-like. 
Pfam
 PF01602; Adaptin_N
 PF02883; Alpha_adaptinC2 
SMART
 SM00809; Alpha_adaptinC2 
PROSITE
 PS50180; GAE 
PRINTS