UniProt Accession

 HEBP1_HUMAN; Q9NRV9; A8K1G2; Q9Y5Z5 

Genbank Protein ID

 AF117615; AF167473; BT007294; AK289877; CH471094; BC016277 

Genbank Nucleotide ID

 AAD32098.1; AAF89618.1; AAP35958.1; BAF82566.1; EAW96295.1; AAH16277.1 

Protein Name

 Heme-binding protein 1 

Protein Synonyms/Alias

 p22HBP 

Gene Name

 HEBP1 

Gene Synonyms/Alias

 HBP 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
49	ATVEVTDKPVDEALR	ubiquitination	[1]
118	DPPAPSDKSVKIEER	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N- methylprotoporphyrin with similar affinities. 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 189 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005576; C:extracellular region; TAS:Reactome.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0020037; F:heme binding; ISS:UniProtKB.
 GO:0007623; P:circadian rhythm; TAS:ProtInc. 

Interpro

 IPR011256; Reg_factor_effector_bac.
 IPR006917; SOUL_haem-bd. 

Pfam

 PF04832; SOUL 

SMART

  

PROSITE

  

PRINTS