UniProt Accession

 E9QMW9_MOUSE; E9QMW9 

Genbank Protein ID

 AC151846 

Genbank Nucleotide ID

  

Protein Name

 Polypyrimidine tract-binding protein 1 

Protein Synonyms/Alias

  

Gene Name

 Ptbp1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
91	VTNLLMLKGKNQAFI	acetylation	[1]
91	VTNLLMLKGKNQAFI	ubiquitination	[2]
136	FSNHKELKTDSSPNQ	acetylation	[3]
136	FSNHKELKTDSSPNQ	ubiquitination	[2]
217	LKIITFTKNNQFQAL	acetylation	[1]
217	LKIITFTKNNQFQAL	ubiquitination	[2]
258	TLRIDFSKLTSLNVK	acetylation	[1, 3]
258	TLRIDFSKLTSLNVK	ubiquitination	[2]
265	KLTSLNVKYNNDKSR	acetylation	[1, 3]
265	KLTSLNVKYNNDKSR	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 353 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006397; P:mRNA processing; IEA:InterPro. 

Interpro

 IPR006536; HnRNP-L_PTB.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

  

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS