CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040513
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutamine-dependent NAD(+) synthetase 
Protein Synonyms/Alias
  
Gene Name
 Nadsyn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
28GNFQRILKSIQIAKGubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 691 AA 
Protein Sequence
MGRKVTVATC ALNQWALDFE GNFQRILKSI QIAKGKGARY RLGPELEICG YGCWDHYHES 60
DTLLHSLQVL AALLDAPATQ DIICDVGMPI MHRNVRYNCR VIFLNRKILL IRPKMALANE 120
GNYRELRWFT PWARSRQTEE YVLPRMLQDL TKQKTVPFGD VVLATQDTCI GSEICEELWT 180
PCSPHVNMGL DGVEIITNAS GSHHVLRKAH TRVDLVTMAT SKNGGIYLLA NQKGCDGDRL 240
YYDGCAMIAM NGSIFAQGTQ FSLDDVEVLT ATLDLEDVRS YRAEISSRNL EATRVNPYPR 300
VTVDFALSVS EDLLEPVSEP VEWTYHRPEE EISLGPACWL WDFLRRSNQA GFFLPLSGGV 360
DSAASACVVY SMCCLVCEAV KSGNQQVLTD VQNLVDESSY TPQDPRELCG RLLTTCYMAS 420
ENSSQETHNR ATKLAQQIGS YHISLNIDPA VKAILGIFSL VTGKFPRFSA HGGSSRENLA 480
LQNVQARIRM VLAYLFAQLS LWSRGARGSL LVLGSANVDE SLLGYLTKYD CSSADINPIG 540
GISKTDLRAF VQLCAERFQL PVLQAILSAP ATAELEPLAD GQVSQMDEED MGMTYTELSI 600
FGRLRKVAKA GPYSMFCKLL NMWKDSCTPR QVAEKVKRFF SKYSINRHKM TTLTPAYHAE 660
NYSPDDNRFD LRPFLYNTRW PWQFLCIDNQ V 691 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
 GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.
 GO:0009435; P:NAD biosynthetic process; IEA:InterPro. 
Interpro
 IPR003010; C-N_Hydrolase.
 IPR014445; Gln-dep_NAD_synthase.
 IPR022310; NAD/GMP_synthase.
 IPR003694; NAD_synthase.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00795; CN_hydrolase
 PF02540; NAD_synthase 
SMART
  
PROSITE
 PS50263; CN_HYDROLASE 
PRINTS