UniProt Accession

 CRH2_YEAST; P32623; D3DLK9; Q6B1R6 

Genbank Protein ID

 U18779; AY693014; L22173; S65964; S66130; BK006939 

Genbank Nucleotide ID

 AAB65002.1; AAT93033.1; AAA34941.1; AAD13975.1; AAB28444.1; DAA07613.1 

Protein Name

 Probable glycosidase CRH2 

Protein Synonyms/Alias

 Congo red hypersensitive protein 2; Unknown transcript 2 protein 

Gene Name

 UTR2 

Gene Synonyms/Alias

 CRH2; YEL040W; SYGP-ORF18 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
140	TRAVWYGKVSARIKT	ubiquitination	[1]
242	TYNATTQKYQYPQTP	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Probable glycosidase that plays a role in cell wall architecture. Required for the transfer of chitin to 1,6-beta- glucan in the cell wall. 

Sequence Annotation

 ACT_SITE 166 166 Nucleophile (By similarity).
 ACT_SITE 170 170 Proton donor (By similarity).
 LIPID 445 445 GPI-anchor amidated asparagine
 CARBOHYD 28 28 N-linked (GlcNAc...) (Potential).
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).
 CARBOHYD 190 190 N-linked (GlcNAc...) (Potential).
 CARBOHYD 196 196 N-linked (GlcNAc...) (Potential).
 CARBOHYD 233 233 N-linked (GlcNAc...) (Potential).
 CARBOHYD 237 237 N-linked (GlcNAc...) (Potential).
 CARBOHYD 261 261 N-linked (GlcNAc...) (Potential).
 CARBOHYD 297 297 N-linked (GlcNAc...) (Potential).
 CARBOHYD 310 310 N-linked (GlcNAc...) (Potential).  

Keyword

 Cell wall; Cell wall biogenesis/degradation; Complete proteome; Glycoprotein; GPI-anchor; Hydrolase; Lipoprotein; Membrane; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 467 AA 

Protein Sequence

Gene Ontology

 GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.
 GO:0000144; C:cellular bud neck septin ring; IDA:SGD.
 GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
 GO:0009277; C:fungal-type cell wall; IDA:SGD.
 GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
 GO:0016757; F:transferase activity, transferring glycosyl groups; IMP:SGD.
 GO:0006037; P:cell wall chitin metabolic process; IMP:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD. 

Interpro

 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR000757; Glyco_hydro_16.
 IPR017168; Glyco_hydro_16_CRH1_prd. 

Pfam

 PF00722; Glyco_hydro_16 

SMART

  

PROSITE

 PS01034; GLYCOSYL_HYDROL_F16 

PRINTS