CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025259
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Rdx 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
114QLFDQVVKTVGLREVubiquitination[1]
139KGYSTWLKLNKKVTQacetylation[2]
150KVTQQDVKKENPLQFacetylation[2]
151VTQQDVKKENPLQFKubiquitination[1]
158KENPLQFKFRAKFFPubiquitination[1]
162LQFKFRAKFFPEDVSubiquitination[1]
218AKYGDYNKEIHKPGYubiquitination[1]
222DYNKEIHKPGYLANDubiquitination[1]
241QRVLEQHKLTKEQWEubiquitination[1]
244LEQHKLTKEQWEERIubiquitination[1]
288GVNYFEIKNKKGTELubiquitination[1]
439QIEEQTVKAQKELEEubiquitination[1]
442EQTVKAQKELEEQTRubiquitination[1]
479RRAAEEAKSAIAKQAubiquitination[1]
484EAKSAIAKQAADQMKubiquitination[1]
514IALLEEAKKKKEEEAubiquitination[1]
527EATEWQHKAFAAQEDubiquitination[1]
537AAQEDLEKTKEELKTubiquitination[1]
599ERVTETQKNERVKKQubiquitination[1]
605QKNERVKKQLQALSSubiquitination[1]
622AQARDETKKTQNDVLubiquitination[1]
623QARDETKKTQNDVLHubiquitination[1]
635VLHAENVKAGRDKYKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 662 AA 
Protein Sequence
RRRAAILPSC LRRLRRVFSQ AAQGSHRRLS ARSPPATTPP PSRASASRRR AGKEPLIFGA 60
IIVYRSEEFL KKVTNKKKKM PKPINVRVTT MDAELEFAIQ PNTTGKQLFD QVVKTVGLRE 120
VWFFGLQYVD SKGYSTWLKL NKKVTQQDVK KENPLQFKFR AKFFPEDVSE ELIQEITQRL 180
FFLQVKEAIL NDEIYCPPET AVLLASYAVQ AKYGDYNKEI HKPGYLANDR LLPQRVLEQH 240
KLTKEQWEER IQNWHEEHRG MLREDSMMEY LKIAQDLEMY GVNYFEIKNK KGTELWLGVD 300
ALGLNIYEHD DKLTPKIGFP WSEIRNISFN DKKFVIKPID KKAPDFVFYA PRLRINKRIL 360
ALCMGNHELY MRRRKPDTIE VQQMKAQARE EKHQKQLERA QLENEKKKRE IAEKEKERIE 420
REKEELMERL RQIEEQTVKA QKELEEQTRK ALELEQERQR AKEEAERLDR ERRAAEEAKS 480
AIAKQAADQM KNQEQLAAEL AEFTAKIALL EEAKKKKEEE ATEWQHKAFA AQEDLEKTKE 540
ELKTVMSAPP PPPPPPVIPP TENEHDEQDE NSAEASAELS SEGVMNHRSE EERVTETQKN 600
ERVKKQLQAL SSELAQARDE TKKTQNDVLH AENVKAGRDK YKTLRQIRQG NTKQRIDEFE 660
AM 662 
Gene Ontology
 GO:0045177; C:apical part of cell; IDA:MGI.
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005856; C:cytoskeleton; IEA:InterPro.
 GO:0019898; C:extrinsic to membrane; IEA:InterPro.
 GO:0030175; C:filopodium; IDA:MGI.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0030027; C:lamellipodium; IDA:MGI.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0001726; C:ruffle; IDA:MGI.
 GO:0032420; C:stereocilium; IDA:MGI.
 GO:0045176; P:apical protein localization; IMP:MGI.
 GO:0030033; P:microvillus assembly; IMP:MGI. 
Interpro
 IPR019749; Band_41_domain.
 IPR019750; Band_41_fam.
 IPR011259; ERM_C_dom.
 IPR000798; Ez/rad/moesin_like.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR019747; FERM_CS.
 IPR000299; FERM_domain.
 IPR018979; FERM_N.
 IPR018980; FERM_PH-like_C.
 IPR008954; Moesin.
 IPR011993; PH_like_dom. 
Pfam
 PF00769; ERM
 PF09380; FERM_C
 PF00373; FERM_M
 PF09379; FERM_N 
SMART
 SM00295; B41 
PROSITE
 PS00660; FERM_1
 PS00661; FERM_2
 PS50057; FERM_3 
PRINTS
 PR00935; BAND41.
 PR00661; ERMFAMILY.