CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011462
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein OPY2 
Protein Synonyms/Alias
 Overproduction-induced pheromone-resistant protein 2 
Gene Name
 OPY2 
Gene Synonyms/Alias
 YPR075C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
164EDDGGMRKDESHTLFubiquitination[1]
287IAEEESDKEIQDLDVubiquitination[1]
353TESPFEDKFEIHDERubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Component of the high-osmolarity glycerol (HOG) pathway involved in mating response and osmotolerance. May act as a membrane anchor for the STE50/STE11 complex. 
Sequence Annotation
 REGION 266 345 STE50-binding.
 MOD_RES 285 285 Phosphoserine.
 MOD_RES 348 348 Phosphoserine.
 CARBOHYD 172 172 N-linked (GlcNAc...) (Potential).
 CARBOHYD 185 185 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Vacuole. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 360 AA 
Protein Sequence
MSSSSKASAS SSLSSTATSS TSATRGSDGC VVCDSTASCP VCASGEYCVM TSLTCDKCPS 60
TYCAKQSDSQ LSSLSSSSSS SSSSNSNEKT SLIVGFTVGI VGGAMLIALV ALYFINKRYW 120
KPKRQKNKAL KLEEASQSYG NEEEYFDDED DDDEDDEDDG GMRKDESHTL FNTSLVPPTL 180
NVPGNRSSAS TTRTRASNIL PIAYIPGVTS GLSTDKLQSK LRSSSKRQNA AGDIRSHITL 240
GSSILDGLDD EDDEHNQVLN KDADDNLITA IRAKPKLVQI AEEESDKEIQ DLDVIEEQTE 300
ADDLSHMAKS EASHGNNDED DDEEGSFILD LEIPESIRES TQGSRTESPF EDKFEIHDER 360 
Gene Ontology
 GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.
 GO:0005887; C:integral to plasma membrane; IDA:SGD.
 GO:0000751; P:cell cycle arrest in response to pheromone; IGI:SGD.
 GO:0090002; P:establishment of protein localization to plasma membrane; IGI:SGD.
 GO:0007231; P:osmosensory signaling pathway; IGI:SGD.
 GO:1900436; P:positive regulation of filamentous growth of a population of unicellular organisms in response to starvation; IMP:SGD. 
Interpro
 IPR018571; Membrane_anchor_Opy2_N. 
Pfam
 PF09463; Opy2 
SMART
  
PROSITE
  
PRINTS