CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013421
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized FAD-linked oxidoreductase Rv2280 
Protein Synonyms/Alias
  
Gene Name
 Rv2280, MT2338 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
354VPRASMPKFLSTARGpupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036
Functional Description
  
Sequence Annotation
 DOMAIN 35 214 FAD-binding PCMH-type.
 CROSSLNK 354 354 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; FAD; Flavoprotein; Isopeptide bond; Oxidoreductase; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 459 AA 
Protein Sequence
MSEMTARFSE IVGNANLLTG DAIPEDYAHD EELTGPPQKP AYAAKPATPE EVAQLLKAAS 60
ENGVPVTARG SGCGLSGAAR PVEGGLLISF DRMNKVLEVD TANQVAVVQP GVALTDLDAA 120
TADTGLRYTV YPGELSSSVG GNVGTNAGGM RAVKYGVARH NVLGLQAVLP TGEIIRTGGR 180
MAKVSTGYDL TQLIIGSEGT LALVTEVIVK LHPRLDHNAS VLAPFADFDQ VMAAVPKILA 240
SGLAPDILEY IDNTSMAALI STQNLELGIP DQIRDSCEAY LLVALENRIA DRLFEDIQTV 300
GEMLMELGAV DAYVLEGGSA RKLIEAREKA FWAAKALGAD DIIDTVVPRA SMPKFLSTAR 360
GLAAAADGAA VGCGHAGDGN VHMAIACKDP EKKKKLMTDI FALAMELGGA ISGEHGVGRA 420
KTGYFLELED PVKISLMRRI KQSFDPAGIL NPGVVFGDT 459 
Gene Ontology
 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro. 
Interpro
 IPR016169; CO_DH_flavot_FAD-bd_sub2.
 IPR016166; FAD-bd_2.
 IPR016167; FAD-bd_2_sub1.
 IPR016164; FAD-linked_Oxase-like_C.
 IPR004113; FAD-linked_oxidase_C.
 IPR006094; Oxid_FAD_bind_N.
 IPR016171; Vanillyl_alc_oxidase_C-sub2. 
Pfam
 PF02913; FAD-oxidase_C
 PF01565; FAD_binding_4 
SMART
  
PROSITE
 PS51387; FAD_PCMH 
PRINTS