| Tag | Content |
|---|
| CPLM ID | CPLM-002032 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor 1-alpha |
Protein Synonyms/Alias | EF-1-alpha |
Gene Name | |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Artemia salina (Brine shrimp) |
NCBI Taxa ID | 85549 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 36 | YKCGGIDKRTIEKFE | methylation | [1] | | 79 | TIDIALWKFETAKYY | methylation | [1] | | 219 | KGWNIERKEGKADGK | methylation | [1] | | 318 | NVKNVSVKELRRGYV | methylation | [1] |
|
Reference | [1] Update on activities at the Universal Protein Resource (UniProt) in 2013. e="String">UniProt Consortium. Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [ PMID: 23161681] |
Functional Description | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. |
Sequence Annotation | NP_BIND 14 21 GTP (By similarity).
NP_BIND 91 95 GTP (By similarity).
NP_BIND 153 156 GTP (By similarity).
MOD_RES 2 2 Blocked amino end (Gly).
MOD_RES 36 36 N6,N6,N6-trimethyllysine.
MOD_RES 55 55 N6-methyllysine (Probable).
MOD_RES 79 79 N6,N6,N6-trimethyllysine.
MOD_RES 219 219 N6,N6,N6-trimethyllysine.
MOD_RES 318 318 N6,N6,N6-trimethyllysine.
MOD_RES 374 374 5-glutamyl glycerylphosphorylethanolamine |
Keyword | Cytoplasm; Direct protein sequencing; Elongation factor; GTP-binding; Methylation; Nucleotide-binding; Phosphoprotein; Protein biosynthesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 462 AA |
Protein Sequence | MGKEKIHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAQEMG KGSFKYAWVL 60
DKLKAERERG ITIDIALWKF ETAKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV 120
GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP PFSEARFEEI KKEVSAYIKK 180
IGYNPAAVAF VPISGWHGDN MLEASDRLPW YKGWNIERKE GKADGKTLLD ALDAILPPSR 240
PTEKPLRLPL QDVYKIGGIG TVPVGRVETG IIKPGMIVTF APANITTEVK SVEMHHESLE 300
QASPGDNVGF NVKNVSVKEL RRGYVASDSK NNPARGSQDF FAQVIVLNHP GQISNGYTPV 360
LDCHTAHIAC KFAEIKEKCD RRTGKTTEAE PKFIKSGDAA MITLVPSKPL CVEAFSDFPP 420
LGRFAVRDMR QTVAVGVIKS VNFKDPTAGK VTKAAEKAGK KK 462 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. GO:0006184; P:GTP catabolic process; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |