CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036258
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Syntaxin-1A 
Protein Synonyms/Alias
  
Gene Name
 Stx1a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
12TQELRTAKDSDDDDDubiquitination[1]
46EIRGFIDKIAENVEEubiquitination[1]
70ASPNPDEKTKEELEEubiquitination[1]
94NKVRSKLKSIEQSIEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 256 AA 
Protein Sequence
MKDRTQELRT AKDSDDDDDV TVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA 60
ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH 120
STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG 180
IIMDSSISKQ ALSEIETRHS EIIKLETSIR ELHDMFMDMA MLVESQETFL NPYPALPPGP 240
EEGRLDLGYP RSCRGR 256 
Gene Ontology
 GO:0043005; C:neuron projection; IDA:MGI.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0030672; C:synaptic vesicle membrane; IDA:MGI.
 GO:0070044; C:synaptobrevin 2-SNAP-25-syntaxin-1a complex; IDA:MGI.
 GO:0070032; C:synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; ISO:MGI.
 GO:0019855; F:calcium channel inhibitor activity; IMP:MGI.
 GO:0001948; F:glycoprotein binding; ISO:MGI.
 GO:0000149; F:SNARE binding; IDA:MGI.
 GO:0017156; P:calcium ion-dependent exocytosis; IMP:MGI.
 GO:0007268; P:synaptic transmission; IEA:InterPro. 
Interpro
 IPR015709; Syntaxin-1.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE
 PF00804; Syntaxin 
SMART
 SM00503; SynN 
PROSITE
 PS50192; T_SNARE 
PRINTS