CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008690
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dicarboxylic amino acid permease 
Protein Synonyms/Alias
  
Gene Name
 DIP5 
Gene Synonyms/Alias
 YPL265W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
7*MKMPLKKMFTSTSPubiquitination[1]
30DHDAYYSKQNPDNFPubiquitination[1]
76SFAVPDGKDENTRLRubiquitination[1, 2]
594ERLKSNGKNMEWFYEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Can transport glutamate, aspartate, glutamine, asparagine, serine, alanine and glycine. 
Sequence Annotation
 MOD_RES 22 22 Phosphoserine.  
Keyword
 Amino-acid transport; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 608 AA 
Protein Sequence
MKMPLKKMFT STSPRNSSSL DSDHDAYYSK QNPDNFPVKE QEIYNIDLEE NNVSSRSSTS 60
TSPSARDDSF AVPDGKDENT RLRKDLKARH ISMIAIGGSL GTGLLIGTGT ALLTGGPVAM 120
LIAYAFVGLL VFYTMACLGE MASYIPLDGF TSYASRYVDP ALGFAIGYTY LFKYFILPPN 180
QLTAAALVIQ YWISRDRVNP GVWITIFLVV IVAINVVGVK FFGEFEFWLS SFKVMVMLGL 240
ILLLFIIMLG GGPNHDRLGF RYWRDPGAFK EYSTAITGGK GKFVSFVAVF VYSLFSYTGI 300
ELTGIVCSEA ENPRKSVPKA IKLTVYRIIV FYLCTVFLLG MCVAYNDPRL LSTKGKSMSA 360
AASPFVVAIQ NSGIEVLPHI FNACVLVFVF SACNSDLYVS SRNLYALAID GKAPKIFAKT 420
SRWGVPYNAL ILSVLFCGLA YMNVSSGSAK IFNYFVNVVS MFGILSWITI LIVYIYFDKA 480
CRAQGIDKSK FAYVAPGQRY GAYFALFFCI LIALIKNFTV FLGHKFDYKT FITGYIGLPV 540
YIISWAGYKL IYKTKVIKST DVDLYTFKEI YDREEEEGRM KDQEKEERLK SNGKNMEWFY 600
EKFLGNIF 608 
Gene Ontology
 GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0015171; F:amino acid transmembrane transporter activity; IDA:SGD. 
Interpro
 IPR004841; AA-permease_dom.
 IPR002293; AA/rel_permease1.
 IPR004762; Amino_acid_permease_fungi.
 IPR004840; Amoino_acid_permease_CS. 
Pfam
 PF00324; AA_permease 
SMART
  
PROSITE
 PS00218; AMINO_ACID_PERMEASE_1 
PRINTS