CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032203
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PMS1 protein homolog 1 
Protein Synonyms/Alias
 cDNA, FLJ79114, highly similar to PMS1 protein homolog 1 
Gene Name
 PMS1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
186AADIVLSKTAETDVLubiquitination[1]
196ETDVLFNKVESSGKNubiquitination[2]
346VKILVPEKSLPCKVSacetylation[3]
512LLQSQIEKRRSQNIKubiquitination[1]
718QLPMYLSKEDIQDIIubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 756 AA 
Protein Sequence
MSFGILKPDL RIVFVHNKAV IWQKSRVSDH KMALMSVLGT AVMNNMESFQ YHSEESQIYL 60
SGFLPKCDAD HSFTSLSTPE RSFIFINSRP VHQKDILKLI RHHYNLKCLK ESTRLYPVFF 120
LKIDVPTADV DVNLTPDKSQ VLLQNKESVL IALENLMTTC YGPLPSTNSY ENNKTDVSAA 180
DIVLSKTAET DVLFNKVESS GKNYSNVDTS VIPFQNDMHN DESGKNTDDC LNHQISIGDF 240
GYGHCSSEIS NIDKNTKNAF QDISMSNVSW ENSQTEYSKT CFISSVKHTQ SENGNKDHID 300
ESGENEEEAG LENSSEISAD EWSRGNILKN SVGENIEPVK ILVPEKSLPC KVSNNNYPIP 360
EQMNLNEDSC NKKSNVIDNK SGKVTAYDLL SNRVIKKPMS ASALFVQDHR PQFLIENPKT 420
SLEDATLQIE ELWKTLSEEE KLKYEEKATK DLERYNSQMK RAIEQESQMS LKDGRKKIKP 480
TSAWNLAQKH KLKTSLSNQP KLDELLQSQI EKRRSQNIKM VQIPFSMKNL KINFKKQNKV 540
DLEEKDEPCL IHNLRFPDAW LMTSKTEVML LNPYRVEEAL LFKRLLENHK LPAEPLEKPI 600
MLTESLFNGS HYLDVLYKMT ADDQRYSGST YLSDPRLTAN GFKIKLIPGV SITENYLEIE 660
GMANCLPFYG VADLKEILNA ILNRNAKEVY ECRPRKVISY LEGEAVRLSR QLPMYLSKED 720
IQDIIYRMKH QFGNEIKECV HGRPFFHHLT YLPETT 756 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0030983; F:mismatched DNA binding; IEA:InterPro.
 GO:0006298; P:mismatch repair; IEA:Compara. 
Interpro
 IPR002099; DNA_mismatch_repair.
 IPR013507; DNA_mismatch_repair_C.
 IPR009071; HMG_box_dom.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 
Pfam
 PF01119; DNA_mis_repair
 PF00505; HMG_box 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS