CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027139
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0719 protein 
Protein Synonyms/Alias
  
Gene Name
 Tomm70a 
Gene Synonyms/Alias
 D16Wsu109e; mKIAA0719 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
141AAKNKGNKYFKAGKYacetylation[1]
186AAFEQLQKWKEVAQDubiquitination[2]
203KAVELNPKYVKALFRacetylation[1]
203KAVELNPKYVKALFRubiquitination[2]
263ENAKEKYKNREPLMPubiquitination[2]
293IISQPMLKGEKSDEDubiquitination[2]
301GEKSDEDKDKEGEALacetylation[1]
311EGEALEVKENSGYLKubiquitination[2]
320NSGYLKAKQYMEEENubiquitination[2]
330MEEENYDKIISECSKacetylation[1]
377LDKVISLKEANVKLRubiquitination[2]
451ACIRLRPKFALAQAQacetylation[1]
451ACIRLRPKFALAQAQubiquitination[2]
481SQVQAAMKGFEEIIKubiquitination[2]
547QWKQDLDKGLELISKubiquitination[2]
581VQRGNMEKAIDMFNKubiquitination[2]
588KAIDMFNKAINLAKSubiquitination[2]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 626 AA 
Protein Sequence
PWRPRPARRR RRTVVMAASK PIEAAMAAAA APGSGNGVGG GGGTAGPGSG AGTLPRWHVA 60
LAIGAPLLLG AGAMYLWSRR RRRREAGGRG DASGLKRNSE RKTPEGRASP ALGSGHHDGS 120
GDSLEMSSLD RAQAAKNKGN KYFKAGKYEQ AIQCYTEAIS LCPTEKNVDL STFYQNRAAA 180
FEQLQKWKEV AQDCTKAVEL NPKYVKALFR RAKAHEKLDN KKECLEDVTA VCILEGFQNE 240
QSMLLADKVL KLLGKENAKE KYKNREPLMP SPQFIKSYFS SFTDDIISQP MLKGEKSDED 300
KDKEGEALEV KENSGYLKAK QYMEEENYDK IISECSKEID AQGKYMAEAL LLRATFYLLI 360
GSANAAKPDL DKVISLKEAN VKLRANALIK RGTMCMQQQQ PMLSTQDFNM AAEIDPMNSD 420
VYHHRGQLKI LLDLVEEAVA DFDACIRLRP KFALAQAQKC FALYRQAYTA NNSSQVQAAM 480
KGFEEIIKKF PRCAEGYALY AQALTDQQQF GKADEMYDKC IDLEPDNATT YVHKGLLQLQ 540
WKQDLDKGLE LISKAIEIDN KCDFAYETMG TIEVQRGNME KAIDMFNKAI NLAKSEMEMA 600
HLYSLCDAAH AQTEVAKKYG LKPPTL 626 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI. 
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF13174; TPR_6
 PF13181; TPR_8 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS