| Tag | Content |
|---|
| CPLM ID | CPLM-000638 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Endophilin-A2 |
Protein Synonyms/Alias | Endophilin-2; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1; SH3p8 |
Gene Name | Sh3gl1 |
Gene Synonyms/Alias | Sh3p8 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 241 | EELADKLKRRVREAS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). |
Sequence Annotation | DOMAIN 18 249 BAR.
DOMAIN 306 365 SH3.
REGION 1 21 Membrane-binding amphipathic helix (By
REGION 60 87 Required for dimerization upon membrane
REGION 218 254 Interaction with ARC.
MOD_RES 288 288 Phosphoserine (By similarity). |
Keyword | 3D-structure; Cell junction; Cell projection; Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Lipid-binding; Membrane; Phosphoprotein; Reference proteome; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 368 AA |
Protein Sequence | MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFREMEKKV DITSKAVAEV LVRTIEYLQP 60
NPASRAKLTM LNTVSKIRGQ VKNPGYPQSE GLLGECMVRH GKELGGESNF GDALLDAGES 120
MKRLAEVKDS LDIEVKQNFI DPLQNLCDKD LKEIQHHLKK LEGRRLDFDY KKKRQGKIPD 180
EELRQALEKF EESKEVAETS MHNLLETDIE QVSQLSALVD AQLDYHRQAV QILEELADKL 240
KRRVREASSR PRREFKPRPQ EPFELGELEQ PNGGFPCASA PKITASSSFR SGDKPTRTPS 300
KSMPPLDQPS CKALYDFEPE NDGELGFREG DLITLTNQID ENWYEGMLHG QSGFFPLSYV 360
QVLVPLPQ 368 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |