UniProt Accession

 INO1_MYCS2; A0R7G6; I7GGA1 

Genbank Protein ID

 CP000480; CP001663 

Genbank Nucleotide ID

 ABK72827.1; AFP43146.1 

Protein Name

 Inositol-3-phosphate synthase 

Protein Synonyms/Alias

 IPS; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthase 

Gene Name

 ino1 

Gene Synonyms/Alias

 MSMEG_6904; MSMEI_6720 

Created Date

 July 27, 2013 

Organism

 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 

NCBI Taxa ID

 246196 

Lysine Modification

Position	Peptide	Type	References
65	AAFDVDAKKVGFDLS	pupylation	[1, 2, 3]

Reference

 [1] Proteasomal protein degradation in Mycobacteria is dependent upon a prokaryotic ubiquitin-like protein.
 Burns KE, Liu WT, Boshoff HI, Dorrestein PC, Barry CE 3rd.
 J Biol Chem. 2009 Jan 30;284(5):3069-75. [PMID: 19028679]
 [2] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036]
 [3] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657] 

Functional Description

 Catalyzes the conversion of glucose 6-phosphate to 1D- myo-inositol 3-phosphate (By similarity). 

Sequence Annotation

 CROSSLNK 65 65 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 Complete proteome; Inositol biosynthesis; Isomerase; Isopeptide bond; Reference proteome; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 363 AA 

Protein Sequence

Gene Ontology

 GO:0004512; F:inositol-3-phosphate synthase activity; IEA:EC.
 GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-KW.
 GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro. 

Interpro

 IPR002587; Myo-inos-1-P_Synthase.
 IPR017815; Myo-inos-1-P_Synthase_actino.
 IPR013021; Myo-inos-1-P_Synthase_GAPDH.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF01658; Inos-1-P_synth
 PF07994; NAD_binding_5 

SMART

  

PROSITE

  

PRINTS