CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045417
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 551 
Protein Synonyms/Alias
  
Gene Name
 ZNF551 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
72KGNTPTQKTHLSEIKubiquitination[1, 2]
79KTHLSEIKMCVPVLKubiquitination[1]
102QTTSPVQKSYLGSTSubiquitination[3]
133YNEEEPWKRKVDEATubiquitination[1]
135EEEPWKRKVDEATFVubiquitination[1, 2]
263CEESFSKKCHLILHKubiquitination[1]
319CRKTFSYKSNLIEHQubiquitination[1, 3]
342YECGECGKSFRQSSSubiquitination[1, 2]
403CGKSFSCKSELIQHQubiquitination[1, 2]
459CEKSFSRKFILIQHQubiquitination[1]
482YECSECGKSFTRKSDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 556 AA 
Protein Sequence
MTFEDVAIYF SQEEWELLDE SQRFLYCDVM LENFAHVTSL GYCHGMENEA IASEQSVSIQ 60
VRTSKGNTPT QKTHLSEIKM CVPVLKDILP AAEHQTTSPV QKSYLGSTSM RGFCFSADLH 120
QHQKHYNEEE PWKRKVDEAT FVTGCRFHVL NYFTCGEAFP APTDLLQHEA TPSGEEPHSS 180
SSKHIQAFFN AKSYYKWGEY RKASSHKHTL VQHQSVCSEG GLYECSKCEK AFTCKNTLVQ 240
HQQIHTGQKM FECSECEESF SKKCHLILHK IIHTGERPYE CSDREKAFIH KSEFIHHQRR 300
HTGGVRHECG ECRKTFSYKS NLIEHQRVHT GERPYECGEC GKSFRQSSSL FRHQRVHSGE 360
RPYQCCECGK SFRQIFNLIR HRRVHTGEMP YQCSDCGKSF SCKSELIQHQ RIHSGERPYE 420
CRECGKSFRQ FSNLIRHRSI HTGDRPYECS ECEKSFSRKF ILIQHQRVHT GERPYECSEC 480
GKSFTRKSDL IQHRRIHTGT RPYECSECGK SFRQRSGLIQ HRRLHTGERP YECSECGKSF 540
SQSASLIQHQ RVHTGE 556 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS