UniProt Accession

 SAN_DROME; Q9NHD5 

Genbank Protein ID

 AF225902; AE013599; AY070826 

Genbank Nucleotide ID

 AAF34715.1; AAG22284.1; AAL48448.1 

Protein Name

 Probable N-acetyltransferase san 

Protein Synonyms/Alias

 Protein separation anxiety 

Gene Name

 san 

Gene Synonyms/Alias

 span; CG12352 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
152	ADAHVLQKTLRRTAP	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. 

Sequence Annotation

 DOMAIN 6 155 N-acetyltransferase.
 MOD_RES 47 47 N6-acetyllysine; by autocatalysis  

Keyword

 Acetylation; Acyltransferase; Cell cycle; Complete proteome; Cytoplasm; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 184 AA 

Protein Sequence

Gene Ontology

 GO:0008280; C:cohesin core heterodimer; IDA:UniProtKB.
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0031248; C:protein acetyltransferase complex; IPI:UniProtKB.
 GO:0008080; F:N-acetyltransferase activity; ISS:UniProtKB.
 GO:0046331; P:lateral inhibition; IMP:FlyBase.
 GO:0007064; P:mitotic sister chromatid cohesion; IMP:FlyBase.
 GO:0048812; P:neuron projection morphogenesis; IMP:FlyBase. 

Interpro

 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 

Pfam

 PF00583; Acetyltransf_1 

SMART

  

PROSITE

 PS51186; GNAT 

PRINTS