CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016784
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dynactin subunit 4 
Protein Synonyms/Alias
 Dynactin subunit p62 
Gene Name
 Dctn4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
181MPLAFSDKYSLGTRLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 414 414 Phosphothreonine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 467 AA 
Protein Sequence
MASLLQSERV LYLVQGEKKV RAPLSQLYFC RYCSELRSLE CVSHEVDSHY CPSCLENMPS 60
AEAKLKKNRC ANCFDCPGCM HTLSTRATSI STQLPDDPAK TTMKKAYYLA CGFCRWTSRD 120
VGMADKSVAS GGWQEPENPH TQRMNKLIEY YQQLAQKEKV ERDRKKLARR RNYMPLAFSD 180
KYSLGTRLQR PRAGASISTL AGLSLREGED QKEVKIEPAQ AVAEVEPLPE DYYTRPVNLT 240
EVTTLQQRLL QPDLQPVSAS QLYPRHKHLL IKRSLRCRKC EHNLSKPEFN PTSIKFKIQL 300
VAVNYIPEVR IMSIPNLRYM KESQVLLTLT NPVENLTHVT LLECDEGDPD NINSTAKVVV 360
PPKELILAGK DAAAEYDELA EPQDFQDDPD IVAFRKANKV GIFIKVTPQR EEGEVTVCFK 420
MKHDFKNLAA PIRPVEEGDQ GTEVIWLTQH VELSFGPLLP 460 
Gene Ontology
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell. 
Interpro
 IPR008603; Dynactin_p62. 
Pfam
 PF05502; Dynactin_p62 
SMART
  
PROSITE
  
PRINTS