UniProt Accession

 B5BUI8_HUMAN; B5BUI8 

Genbank Protein ID

 AB451424 

Genbank Nucleotide ID

 BAG70238.1 

Protein Name

 Dual specificity phosphatase 3 

Protein Synonyms/Alias

  

Gene Name

 DUSP3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
53	QDIPKLQKLGITHVL	ubiquitination	[1]
116	IDQALAQKNGRVLVH	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Hydrolase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 

Interpro

 IPR020417; Atypical_DUSP.
 IPR020405; Atypical_DUSP_famA.
 IPR000340; Dual-sp_phosphatase_cat-dom.
 IPR020422; Dual-sp_phosphatase_subgr_cat.
 IPR024950; DUSP.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS. 

Pfam

 PF00782; DSPc 

SMART

 SM00195; DSPc 

PROSITE

 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50054; TYR_PHOSPHATASE_DUAL 

PRINTS

 PR01908; ADSPHPHTASE.
 PR01909; ADSPHPHTASEA.