UniProt Accession

 D3YWS3_MOUSE; D3YWS3 

Genbank Protein ID

 AC165888 

Genbank Nucleotide ID

  

Protein Name

 Profilin 

Protein Synonyms/Alias

  

Gene Name

 Pfn2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
91	CTMDIRTKSQGGEPT	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Actin-binding; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 110 AA 

Protein Sequence

Gene Ontology

 GO:0043195; C:terminal bouton; IDA:MGI.
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
 GO:0030837; P:negative regulation of actin filament polymerization; IDA:MGI.
 GO:0030838; P:positive regulation of actin filament polymerization; IMP:MGI.
 GO:2000300; P:regulation of synaptic vesicle exocytosis; IMP:MGI. 

Interpro

 IPR005454; Profilin_chordates.
 IPR027310; Profilin_CS.
 IPR005455; Profilin_eukaryotes/bac. 

Pfam

 PF00235; Profilin 

SMART

  

PROSITE

 PS00414; PROFILIN 

PRINTS

 PR01639; PROFILINMAML.