CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026156
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-dependent Clp protease, ATP-binding subunit (ClpA) 
Protein Synonyms/Alias
  
Gene Name
 TTHA0542 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
317EYHRYIEKDAALERRacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Hydrolase; Nucleotide-binding; Protease; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 736 AA 
Protein Sequence
MNRYDDRARL VFHYAREEGS RLGHSMIGPE HLLLGLMREG GTAARILQEY GASLEAMRRM 60
VEELVGRGEG GRTGEPPAIT PRARRVMELA SAEARNMGSP VIGTEHILLG IIREGDGIAY 120
RILSHFAKDV DAIRWRVLAM AEGREREKPV NTPFLDEYGR DLTKEAREGK LDPVIGRQEE 180
INRVIQILAR RTKNNPVLIG DPGVGKTAIV EGLAQAIVEG RVPPILKGAR VVAIDLAGVV 240
AGTKYRGEFE ERLRQIIEEL KNAKVIAFID ELHTLIGAGG AEGTLDAANI LKPALARGEI 300
QVIGATTTGE YHRYIEKDAA LERRFQPVIV LEPSPEETLE ILKGLRPRYE AHHGVIIPDE 360
ILELAVKIGI RSLPGRNFPD KAIDLIDEAA SRVRLNASLG LPVAEEEDGT PIVTREDVEA 420
VVDSWGGVYV DDKDDEKLMR LEEELRKRVV GQEEAIRALA NALRRARVGL GGRTRVAASF 480
LFVGQSGVGK TQLAKALAEV LFGSERALIR FDMSEFQEPH SISKLIGAPP GYVGYEQGGR 540
LTEAVRRQPF SVVLLDEIEK AHPDIYNTFL QVLDEGRLTD GMGRTVDFRR VILIMTSNTG 600
YNVGPAIGFT SKEVDTESPL KALFTPEFLD RLDEVIRFRP LTEEELVRVA EMMLEDIRKE 660
LQARDVQVSF APELARFLVD QAPKTGSARA LRSVLRERIE DPLAVALLRK PTGRIHVSVE 720
GGQVAFHEVE GEELLV 736 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR013093; ATPase_AAA-2.
 IPR003959; ATPase_AAA_core.
 IPR018368; Chaperonin_ClpA/B_CS.
 IPR001270; Chaprnin_ClpA/B.
 IPR019489; Clp_ATPase_C.
 IPR004176; Clp_N.
 IPR023150; Dbl_Clp-N.
 IPR027417; P-loop_NTPase.
 IPR025662; Sigma_54_int_dom_ATP-bd_1. 
Pfam
 PF00004; AAA
 PF07724; AAA_2
 PF02861; Clp_N
 PF10431; ClpB_D2-small 
SMART
 SM00382; AAA
 SM01086; ClpB_D2-small 
PROSITE
 PS00870; CLPAB_1
 PS00675; SIGMA54_INTERACT_1 
PRINTS
 PR00300; CLPPROTEASEA.