CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021794
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA 3'-terminal phosphate cyclase-like protein 
Protein Synonyms/Alias
  
Gene Name
 Rcl1 
Gene Synonyms/Alias
 Rnac 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
175LFSCPVRKVLKPVQLubiquitination[1]
231YIYTDHMKGVSSGKSubiquitination[1]
281DLGRNCAKLLLEEIYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 373 AA 
Protein Sequence
MATQAHSLSY AGCNFLRQRL VLSTLSGRPV KIRRIRARDD NPGLRDFEAS FIRLLDKITN 60
GSRIEINQTG TTLYYQPGLL YGGSVEHDCS VLRGIGYYLE ALLCLAPFMK HPLKIVLRGV 120
TNDQVDPSVD VLKATALPLL KQFGIDGESF ELKILRRGMP PGGGGEVLFS CPVRKVLKPV 180
QLTDPGKIKR IRGMAYSVRV SPQMANRIVD SARSILNKFI PDIYIYTDHM KGVSSGKSPG 240
FGLSLVAETT NGTFLSAELA SNPQGQGAAV LPEDLGRNCA KLLLEEIYRG GCVDSTNQSL 300
VLLLMTLGQQ DVSKVLLGPL SPYTIEFLRH LKSFFQVMFK VETKPCGEEL KGGDKVLMTC 360
VGIGFSNLSK TLK 373 
Gene Ontology
 GO:0005730; C:nucleolus; IDA:MGI.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0006364; P:rRNA processing; ISA:MGI. 
Interpro
 IPR013791; RNA3'-term_phos_cycl_insert.
 IPR023797; RNA3'_phos_cyclase_dom.
 IPR000228; RNA3'_term_phos_cyc.
 IPR016443; RNA3'_term_phos_cyc_type_2.
 IPR020719; RNA3'_term_phos_cycl-like_CS.
 IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b. 
Pfam
 PF01137; RTC
 PF05189; RTC_insert 
SMART
  
PROSITE
 PS01287; RTC 
PRINTS