| Tag | Content |
|---|
| CPLM ID | CPLM-005369 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein STE50 |
Protein Synonyms/Alias | |
Gene Name | STE50 |
Gene Synonyms/Alias | YCL032W; YCL32W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 312 | VIIFKNLKQQGLHPA | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in growth arrest during conjugation. May interact with the G protein alpha subunit. |
Sequence Annotation | DOMAIN 24 108 SAM.
DOMAIN 233 327 Ras-associating.
MOD_RES 202 202 Phosphoserine.
MOD_RES 244 244 Phosphothreonine.
MOD_RES 248 248 Phosphoserine. |
Keyword | 3D-structure; Cell cycle; Complete proteome; Growth arrest; Pheromone response; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 346 AA |
Protein Sequence | MEDGKQAINE GSNDASPDLD VNGTILMNNE DFSQWSVDDV ITWCISTLEV EETDPLCQRL 60
RENDIVGDLL PELCLQDCQD LCDGDLNKAI KFKILINKMR DSKLEWKDDK TQEDMITVLK 120
NLYTTTSAKL QEFQSQYTRL RMDVLDVMKT SSSSSPINTH GVSTTVPSSN NTIIPSSDGV 180
SLSQTDYFDT VHNRQSPSRR ESPVTVFRQP SLSHSKSLHK DSKNKVPQIS TNQSHPSAVS 240
TANTPGPSPN EALKQLRASK EDSCERILKN AMKRHNLADQ DWRQYVLVIC YGDQERLLEL 300
NEKPVIIFKN LKQQGLHPAI MLRRRGDFEE VAMMNGSDNV TPGGRL 346 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0019887; F:protein kinase regulator activity; IPI:SGD. GO:0032093; F:SAM domain binding; IDA:SGD. GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW. GO:0034605; P:cellular response to heat; IMP:SGD. GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD. GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD. GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IPI:SGD. GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD. |
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SMART | |
PROSITE | |
PRINTS | |