CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020518
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein NipSnap homolog 3B 
Protein Synonyms/Alias
 NipSnap3B; NipSnap-related protein; Protein NipSnap homolog 3A; NipSnap3A 
Gene Name
 Nipsnap3b 
Gene Synonyms/Alias
 Nipsnap3a 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
45EFRTYFLKPSKTNEFacetylation[1]
48TYFLKPSKTNEFLENacetylation[1]
105AVRKALAKDKEWQERacetylation[1]
107RKALAKDKEWQERFLacetylation[1]
166ALWGNAFKRAVNAHVacetylation[2, 3, 4]
166ALWGNAFKRAVNAHVsuccinylation[4]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [3] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Mitochondrion; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 247 AA 
Protein Sequence
MLALRSGLRT ALAPRVLTPQ VCSPFATGPR QSNGTFYEFR TYFLKPSKTN EFLENFKNSV 60
HLRTAHSEMI GYWTVEFGGR TNRVFHIWKY DNFAHRTAVR KALAKDKEWQ ERFLIPNLAF 120
IDKQEVEITY LVPWCKIGTP PKEGVYELAT FQMKPGGPAL WGNAFKRAVN AHVELGYSTL 180
VGVFHTEYGA LNRVHVLWWN ESADSRAAGR HWSHEDPRVV AAVRESVSYL ESQQNTFLIP 240
TSFSPLK 247 
Gene Ontology
 GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI. 
Interpro
 IPR011008; Dimeric_a/b-barrel.
 IPR012577; NIPSNAP. 
Pfam
 PF07978; NIPSNAP 
SMART
  
PROSITE
  
PRINTS